Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13196458 | 0.94 | NAMPT (0.40) | CNR2EGLN1PKMKDM4EPOLB | |
| SCHEMBL13196438 | 0.91 | CNR2 (0.37) | CNR2EGLN1PKMKDM4EPOLB | |
| SCHEMBL13196447 | 0.91 | CNR2 (0.37) | CNR2EGLN1PKMKDM4EPOLB | |
| SCHEMBL13196444 | 0.90 | CNR2 (0.40) | CNR2EGLN1PKMKDM4EPOLB | |
| SCHEMBL2780892 | 0.87 | CNR2 (0.44) | CNR2PKMKDM4EPOLBTSHR | |
| SCHEMBL13196442 | 0.84 | ALDH1A1 (0.41) | CNR2PKMKDM4EPOLBTSHR | |
| SCHEMBL13196461 | 0.84 | PKM (0.38) | CNR2PKMKDM4EPOLBPKLR | |
| SCHEMBL13196575 | 0.84 | CNR2 (0.40) | CNR2EGLN1KDM4EPOLBTSHR | |
| SCHEMBL2784556 | 0.82 | PKM (0.41) | CNR2PKMPOLBTSHRALDH1A1 | |
| SCHEMBL13196558 | 0.82 | NAMPT (0.39) | CNR2EGLN1POLBCYP2C9NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |