Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 19/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350528 | 0.77 | HSD11B1 (0.58) | HSD11B1CYP2D6ALDH1A1 | |
| SCHEMBL349845 | 0.76 | HSD11B1 (0.58) | HSD11B1CYP2D6 | |
| SCHEMBL18025755 | 0.69 | PDK2 (0.46) | ALDH1A1 | |
| SCHEMBL348724 | 0.66 | HSD11B1 (1.00) | HSD11B1ALDH1A1 | |
| SCHEMBL349249 | 0.65 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL349025 | 0.65 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL350439 | 0.64 | HSD11B1 (1.00) | HSD11B1ALDH1A1 | |
| SCHEMBL351050 | 0.64 | HSD11B1 (1.00) | HSD11B1ALDH1A1 | |
| SCHEMBL349468 | 0.64 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL31623079 | 0.64 | HTR1A (0.77) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058288-B2 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION (US) | 2011-11-15 | — | — | US | disclosed |