Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780892 | 0.90 | CNR2 (0.44) | CNR2HTR6POLBHTT | |
| SCHEMBL13196447 | 0.90 | CNR2 (0.37) | NAMPTCNR2ELANEPOLBAVPR1B | |
| SCHEMBL13196442 | 0.89 | ALDH1A1 (0.41) | NAMPTCNR2CYP2C9POLB | |
| SCHEMBL2784556 | 0.85 | PKM (0.41) | CNR2CYP2C9HTR6POLB | |
| SCHEMBL2783111 | 0.83 | POLB (0.48) | CNR2POLBHTT | |
| SCHEMBL13196575 | 0.82 | CNR2 (0.40) | CNR2CYP2C9POLBHTTEGLN1 | |
| SCHEMBL13196604 | 0.82 | CNR2 (0.40) | NAMPTCNR2CYP2C9POLBEGLN1 | |
| SCHEMBL2780191 | 0.82 | ALDH1A1 (0.39) | NAMPTCNR2HTR6POLBAVPR1B | |
| SCHEMBL2780358 | 0.81 | CNR2 (0.39) | CNR2POLB | |
| SCHEMBL2782395 | 0.81 | HTT (0.39) | NAMPTCNR2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |