SCHEMBL131968

SCHEMBL131968

CC(C)(C)c1ccc([Si](Cl)(Cl)Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
LMNA P02545 1/20 0.46
TYR P14679 1/20 0.46
KIF11 P52732 3/20 0.44
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
ALDH1A1 P00352 5/20 0.38
MITF O75030 1/20 0.38
TP53 P04637 1/20 0.38
KMT2A Q03164 1/20 0.38
HPGD P15428 2/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
HDAC1 Q13547 1/20 0.37
SLC22A2 O15244 1/20 0.37
SLC22A1 O15245 1/20 0.37
SLC22A3 O75751 1/20 0.37
POLB P06746 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22229723 0.84 TSHR (0.48) TSHRLMNATYRKIF11NPC1
SCHEMBL10319202 0.82 TSHR (0.46) TSHRLMNATYRKIF11NPC1
SCHEMBL8382993 0.82 TSHR (0.46) TSHRLMNATYRKIF11NPC1
SCHEMBL15084991 0.82 PDE2A (0.46) KIF11NPC1RAB9AKMT2AKDM4E
SCHEMBL16884601 0.78 TSHR (0.52) TSHRLMNATYRKIF11NPC1
SCHEMBL10318784 0.77 TSHR (0.41) TSHRLMNATYRKIF11NPC1
SCHEMBL424728 0.76 TSHR (0.73) TSHRLMNATYRKIF11NPC1
SCHEMBL20332823 0.76 TSHR (0.50) TSHRLMNATYRKIF11NPC1
SCHEMBL17678821 0.76 TSHR (0.50) TSHRLMNATYRKIF11NPC1
SCHEMBL3175501 0.76 KIF11 (0.48) TSHRKIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4481500-A1 TONER, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND METHOD OF MANUFACTURING PRINTED MATTER Ricoh Company, Ltd. (JP) 2024-12-25 EP disclosed
US-20240377770-A1 TONER, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND METHOD OF MANUFACTURING PRINTED MATTER RICOH COMPANY, LTD. (JP) 2024-11-14 US disclosed
US-20230205105-A1 TONER, IMAGE FORMING APPARATUS, IMAGE FORMATION METHOD, AND PRINTED MATTER MANUFACTURING METHOD RICOH COMPANY, LTD. (JP) 2023-06-29 US disclosed
EP-3825766-A1 TONER SET, IMAGE FORMING METHOD, AND SCRATCH IMAGE FORMED PRODUCT Ricoh Company, Ltd. (JP) 2021-05-26 EP disclosed
US-10254668-B2 Toner for electrophotography, developer for electrophotography, image forming apparatus, and process cartridge RICOH COMPANY, LTD (JP) 2019-04-09 US disclosed
US-20180067409-A1 TONER FOR ELECTROPHOTOGRAPHY, DEVELOPER FOR ELECTROPHOTOGRAPHY, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2018-03-08 US disclosed
EP-2367060-B1 Toner, method of manufacturing toner and image forming method RICOH CO LTD (JP) 2016-11-02 EP disclosed
US-9256147-B2 Toner, and image forming method and process cartridge using the toner RICOH COMPANY, LTD. (JP) 2016-02-09 US disclosed
EP-1617294-B1 Toner for developing electrostatic image, method for producing the same, developer, image forming apparatus, process cartridge, and image forming method RICOH CO LTD (JP) 2015-12-23 EP disclosed
US-9152064-B2 Method of preparing developer, developer for electrophotography, process cartridge and image forming apparatus RICOH COMPANY, LTD. (JP) 2015-10-06 US disclosed
EP-1043630-A2 Toner, method of producting the toner, image formation method using the toner, and toner container Ricoh Company, Ltd. (JP) 2000-10-11 EP disclosed
US-6074795-A BINDER RESINS, COLORS AND RELEASING AGENTS WITH ABSORPTION RICOH COMPANY, LTD. (JP) 2000-06-13 US disclosed
EP-0997786-A1 Toner and two-component developer for electrophotographic process and image formation method and image formation apparatus using the toner Ricoh Company, Ltd. (JP) 2000-05-03 EP disclosed
EP-0974871-A1 Toner and developer including the same MITA INDUSTRIAL CO. LTD. (JP) 2000-01-26 EP disclosed
EP-0974870-A1 Toner for amorphous silicon photoreceptor and developer including the same MITA INDUSTRIAL CO. LTD. (JP) 2000-01-26 EP disclosed
US-5716748-A SHELL, CORE POLYMER NIPPON ZEON CO., LTD. (JP) 1998-02-10 US disclosed
US-4985328-A Metal Complex Charge Control Agents HITACHI CHEMICAL CO., LTD. (JP) 1991-01-15 US disclosed
EP-0360617-A2 Dry toner, dry developer and process for forming images Hitachi Chemical Co., Ltd. (JP) 1990-03-28 EP disclosed
US-4686166-A HIGH IMAGE DENSITY, ANTIFOGGING AGENT HITACHI CHEMICAL CO. (JP) 1987-08-11 US disclosed
US-4585723-A SILICON DIOXIDE PARTICLES MADE HYDROPHOBIC KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-29 US disclosed