SCHEMBL1319783

SCHEMBL1319783

O=P(O)(OCCc1ccccc1)OCCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.64
ANPEP P15144 2/20 0.47
ERAP1 Q9NZ08 2/20 0.47
ERAP2 Q6P179 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
CA12 O43570 1/20 0.46
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP3 P08254 1/20 0.46
ACP3 P15309 1/20 0.46
CYP2D6 P10635 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
KEAP1 Q14145 1/20 0.43
FFAR1 O14842 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11752362 0.98 TSHR (0.62) TSHRANPEPERAP1ERAP2TDP1
SCHEMBL28250516 0.89 TSHR (0.53) TSHRANPEPERAP1ERAP2TDP1
SCHEMBL27921183 0.89 TSHR (0.52) TSHRANPEPERAP1ERAP2TDP1
SCHEMBL9053131 0.89 TSHR (0.52) TSHRANPEPERAP1ERAP2TDP1
SCHEMBL3366802 0.89 BTN3A1 (0.52) TSHRANPEPERAP1ERAP2TDP1
SCHEMBL17333279 0.88 TSHR (0.60) TSHRFFAR1
SCHEMBL32660804 0.88 CETP (0.53) TSHR
SCHEMBL516899 0.88 TSHR (0.53) TSHRANPEPERAP1ERAP2TDP1
SCHEMBL27697396 0.87 SRC (0.50) TSHRANPEP
SCHEMBL11757960 0.86 TSHR (0.52) TSHRANPEPERAP1ERAP2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439252-B2 Electrolyte solution for electrochemical device, and electrochemical device FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-08 US disclosed
EP-3500544-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS Huntsman Petrochemical LLC (US) 2019-06-26 EP disclosed
US-20190161418-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS INDORAMA VENTURES OXIDES LLC 2019-05-30 US disclosed
WO-2018034864-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS HUNTSMAN PETROCHEMICAL LLC (US) 2018-02-22 WO disclosed
EP-3192799-A1 5'-POSITION DIBENZYL PHOSPHORIC ACID ESTER OF 5-AZACYTIDINE OR 2'-DEOXY BODY THEREOF Ohara Pharmaceutical Co., Ltd. (JP) 2017-07-19 EP disclosed
US-9670238-B1 5′-dibenzyl phosphates of 5-azacytidine or 2′-deoxy-5-azacytidine OHARA PHARMACEUTICAL CO., LTD. (JP) 2017-06-06 US disclosed
US-20170152275-A1 5'-DIBENZYL PHOSPHATES OF 5-AZACYTIDINE OR 2'-DEOXY-5-AZACYTIDINE OHARA PHARMACEUTICAL CO., LTD. (JP) 2017-06-01 US disclosed
US-20150364792-A1 ELECTROLYTE SOLUTION FOR ELECTROCHEMICAL DEVICE, AND ELECTROCHEMICAL DEVICE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-17 US disclosed
US-8491811-B2 Lubricant for compression refrigerating machine and refrigerating apparatus using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-07-23 US disclosed
US-20110274932-A1 COMPONENT COMPRISING AN INSERT PART AND PLASTICS JACKETING, AND PROCESS FOR PRODUCTION OF THE COMPONENT BASF SE (DE) 2011-11-10 US disclosed
US-6352962-B1 ADDITIVE FOR TRACTION DRIVE FLUID OBTAINED BY HEATING AT LEAST ONE ESTER SELECTED FROM ACIDIC PHOSPHATE ESTER AND PHOSPHITE ESTER AND SUCCINIMIDE DISPERSANT CONTAINING BORON AT TEMPERATURE OF 120 TO 150 DEGREES C. FOR 5 HOURS OR MORE IDEMITSU KOSAN CO., LTD. (JP) 2002-03-05 US disclosed
US-6303546-B1 CONTAINING PHOSPHATE ESTER, BORON-CONTAINING IMIDE BASE DISPERSANT AND BORON-FREE IMIDE BASE DISPERSANT IDEMITSU KOSAN CO., LTD. (JP) 2001-10-16 US disclosed
EP-1142983-A1 Lubricant additive IDEMITSU KOSAN COMPANY LIMITED (JP) 2001-10-10 EP disclosed
EP-1057884-A1 Traction drive fluid IDEMITSU KOSAN COMPANY LIMITED (JP) 2000-12-06 EP disclosed
EP-1057882-A1 Lubricating oil composition for cellulose base wet friction material IDEMITSU KOSAN CO., LTD. (JP) 2000-12-06 EP disclosed
EP-0871454-A4 1998-11-25 EP disclosed
EP-0871454-A1 PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS CEPHALON, INC. (US) 1998-10-21 EP disclosed
US-5639732-A FOR TREATING NERVOUS SYSTEM DISORDERS OR AS ANTIINFLAMMATORY AGENT CEPHALON, INC. (US) 1997-06-17 US disclosed
WO-1997003679-A1 PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS CEPHALON, INC. (US) 1997-02-06 WO disclosed
US-5405736-A Staight or branched chain substituted or unstubstituted dialkyl or diaryl phosphate solvent which is solid below 60 degree centigrade, high melting point than coupler EASTMAN KODAK COMPANY (US) 1995-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170152275-A1 5'-DIBENZYL PHOSPHATES OF 5-AZACYTIDINE OR 2'-DEOXY-5-AZACYTIDINE DUT, DCTD, DPYD TSHR 3273/4885ANPEP 421/4885ERAP1 277/4885
US-20190161418-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS PNPO, SLC19A1, SLC6A12 TSHR 1640/4885ANPEP 1879/4885ERAP1 3853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.