Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10096339 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL13214446 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AADORA2BADORA2A | |
| SCHEMBL10095796 | 0.87 | MTNR1B (0.44) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL10096221 | 0.87 | AS3MT (0.47) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10096332 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL10096348 | 0.84 | MEN1 (0.41) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL10096219 | 0.84 | AR (0.51) | ADORA2BADORA2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10096220 | 0.84 | AR (0.53) | MEN1KMT2AADORA2BADORA2ARAB9A | |
| SCHEMBL10096338 | 0.83 | L3MBTL1 (0.40) | ALDH1A1MEN1KMT2APOLBMAPK1 | |
| SCHEMBL10096222 | 0.83 | AR (0.49) | ADORA2BADORA2ARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781478-B2 | Methods for treating hepatitis C | PTC THERAPEUTICS, INC. (US) | 2010-08-24 | — | — | US | disclosed |