SCHEMBL339060

SCHEMBL339060

CCOC(=O)c1c(C(=O)O)cccc1-c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 6/20 0.48
PTPRC P08575 2/20 0.48
PTPN2 P17706 2/20 0.48
PTPA Q15257 2/20 0.48
PTPRF P10586 1/20 0.48
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
TSHR P16473 1/20 0.45
POLB P06746 2/20 0.44
APEX1 P27695 1/20 0.44
RECQL P46063 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAPT P10636 5/20 0.44
CYP1A2 P05177 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL338153 0.96 TSHR (0.47) PTPN1PTPRCPTPN2PTPAPTPRF
SCHEMBL5572324 0.86 PTPN1 (0.55) PTPN1PTPRCPTPN2PTPAPTPRF
Ether SCHEMBL10413640 0.85 PTPN11 (0.44) PTPN1PTPRCPTPN2PTPAPTPRF
SCHEMBL1346651 0.84 MCL1 (0.42) ALOX15KMT2APTPN11MCL1ALDH1A1
SCHEMBL31121002 0.82 PTPN1 (0.54) PTPN1PTPRCPTPN2PTPAPTPRF
SCHEMBL6462555 0.81 MCL1 (0.40) PTPN1ALOX15PTPN11MCL1ALDH1A1
SCHEMBL87895 0.81 CDC25B (0.49) POLBALOX15KMT2APTPN11MCL1
SCHEMBL338971 0.81 SLC6A3 (0.50) PTPRCCA12CA1CA2CA7
SCHEMBL339059 0.81 SLC6A3 (0.50) PTPRCCA12CA1CA2CA7
Water SCHEMBL6403598 0.79 CDC25B (0.47) POLBALOX15KMT2APTPN11MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1721924-B1 ENDLESS TUBULAR POLYIMIDE FILM GUNZE KK (JP) 2014-12-17 EP disclosed
US-8314204-B2 Endless tubular polyimide film GUNZE LIMITED (JP) 2012-11-20 US disclosed
US-20120040121-A1 ENDLESS TUBULAR POLYIMIDE FILM UBE INDUSTRIES, LTD. (JP) 2012-02-16 US disclosed
US-8097693-B2 Endless tubular polyimide film GUNZE LIMITED (JP) 2012-01-17 US disclosed
US-20070178264-A1 Endless tubular polyimide film GUNZE LIMITED (JP) 2007-08-02 US disclosed
EP-1721924-A1 ENDLESS TUBULAR POLYIMIDE FILM GUNZE LIMITED (JP) 2006-11-15 EP disclosed