Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13199555 | 0.87 | ABCB1 (0.42) | ABCB1CYP3A4L3MBTL1KCNA5 | |
| SCHEMBL13199558 | 0.82 | ABCB1 (0.43) | KMT2AABCB1ALDH1A1CYP3A4KCNA5 | |
| SCHEMBL13199556 | 0.81 | NR3C1 (0.37) | ABCB1KCNA5 | |
| SCHEMBL2012197 | 0.81 | ABCB1 (0.42) | ABCB1ALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL13199561 | 0.76 | ABCB1 (0.45) | ABCB1CYP3A4KCNA5 | |
| SCHEMBL13199622 | 0.75 | ABCB1 (0.44) | ABCB1ALDH1A1CYP3A4KCNA5 | |
| SCHEMBL13199624 | 0.74 | ABCB1 (0.44) | ABCB1CYP3A4KCNA5 | |
| SCHEMBL13199632 | 0.74 | NR1D1 (0.36) | KMT2AABCB1ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL2889489 | 0.73 | NPC1 (0.45) | KMT2AALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL5987814 | 0.73 | ALDH1A1 (0.42) | KMT2AABCB1ALDH1A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718629-B1 | Benzopyran compounds useful for the treatment of arrhytmia | NISSAN CHEMICAL IND LTD (JP) | 2012-12-26 | — | — | EP | disclosed |
| US-7781483-B2 | Benzopyran compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-24 | — | — | US | disclosed |
| US-7781483-B2 | Benzopyran compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-24 | — | — | US | disclosed |