⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18996006 | 0.76 | GABRG2 (0.30) | — | |
| SCHEMBL30702431 | 0.72 | HSP90AA1 (0.32) | — | |
| SCHEMBL28785903 | 0.72 | HSP90AA1 (0.32) | — | |
| SCHEMBL28465601 | 0.68 | — | — | |
| SCHEMBL20162926 | 0.68 | — | — | |
| SCHEMBL4884779 | 0.67 | HCAR2 (0.36) | — | |
| SCHEMBL2023933 | 0.66 | CYP1A2 (0.37) | — | |
| SCHEMBL14311954 | 0.66 | ADORA3 (0.32) | — | |
| SCHEMBL17811376 | 0.64 | PDE3B (0.36) | — | |
| SCHEMBL25877017 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772263-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-20090156586-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION | 2009-06-18 | — | — | US | disclosed |
| US-7524842-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2009-04-28 | — | — | US | disclosed |
| US-20070197564-A1 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION | 2007-08-23 | — | — | US | disclosed |