Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylformamide SCHEMBL28802744 | 0.88 | KDM4E (0.32) | — | |
| SCHEMBL14311954 | 0.84 | ADORA3 (0.32) | — | |
| SCHEMBL28331832 | 0.80 | MAPK1 (0.36) | — | |
| SCHEMBL2023933 | 0.80 | CYP1A2 (0.37) | — | |
| SCHEMBL30717975 | 0.80 | TP53 (0.35) | — | |
| SCHEMBL30717979 | 0.80 | TP53 (0.35) | — | |
| SCHEMBL29437387 | 0.72 | JUN (0.31) | — | |
| SCHEMBL23850062 | 0.70 | TRPV1 (0.32) | HCAR2 | |
| SCHEMBL30702431 | 0.69 | HSP90AA1 (0.32) | — | |
| SCHEMBL28785903 | 0.69 | HSP90AA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384741-B | A kind of salt and preparation method thereof of cyclin dependant kinase inhibitors | 诺华有限公司 | 2019-11-19 | — | — | CN | claimed |
| US-20250388593-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2025-12-25 | — | — | US | disclosed |
| WO-2023202625-A1 | FGFR2 INHIBITOR AND METHOD FOR USING SAME | 深圳福沃药业有限公司 | 2023-10-26 | — | — | WO | disclosed |
| CN-116903628-A | FGFR2 inhibitors and methods of use | 深圳福沃药业有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-105384741-B | A kind of salt and preparation method thereof of cyclin dependant kinase inhibitors | 诺华有限公司 | 2019-11-19 | — | — | CN | disclosed |
| CN-105384741-B | A kind of salt and preparation method thereof of cyclin dependant kinase inhibitors | 诺华有限公司 | 2019-11-19 | — | — | CN | disclosed |
| CN-110156793-A | Rui Boxini monosuccinic acid salt novel crystal forms and preparation method | 安礼特（上海）医药科技有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-105111215-B | A kind of crystal form and preparation method thereof of cyclin-dependent kinase inhibitor | 苏州晶云药物科技股份有限公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-108290899-A | SUBSTITUTED PYRROLOPYRIMIDINE COMPOUND AND APPLICATION THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-104672241-B | Pyrrolo- [2,3-d] pyrimidines and application thereof | 王磊 | 2018-04-24 | — | — | CN | disclosed |
| CN-106008533-B | CDK inhibitor | G1治疗公司 | 2018-01-23 | — | — | CN | disclosed |
| CN-106967074-A | CDK inhibitor | G1治疗公司 | 2017-07-21 | — | — | CN | disclosed |
| CN-103936745-B | Cdk inhibitors | G1治疗公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-106008533-A | Cdk inhibitors | G1治疗公司 | 2016-10-12 | — | — | CN | disclosed |
| US-20080139588-A1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | THE PROCTER & GAMBLE COMPANY | 2008-06-12 | — | — | US | disclosed |
| US-7319102-B1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139588-A1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | DPYD, IL1B, IL6 | HCAR2 825/4885 |
| US-20250388593-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | CRBN, CUL1, CBL | HCAR2 3159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.