Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13196704 | 1.00 | SLC6A3 (0.45) | SLC6A3RECQLSLC6A4CA1CA2 | |
| SCHEMBL21057760 | 0.91 | RECQL (0.46) | SLC6A3RECQLSLC6A4CA1CA2 | |
| SCHEMBL2800532 | 0.81 | LMNA (0.37) | ALDH1A1TDP1LMNA | |
| SCHEMBL21057706 | 0.77 | RECQL (0.36) | SLC6A3RECQLCA1CA2CA4 | |
| SCHEMBL13200505 | 0.76 | CYP2D6 (0.40) | CYP2D6ALDH1A1TDP1LMNA | |
| SCHEMBL13196706 | 0.76 | CYP2D6 (0.40) | CYP2D6ALDH1A1TDP1LMNA | |
| SCHEMBL21057955 | 0.76 | CYP2D6 (0.50) | SLC6A3SLC6A4CA1CA2CA4 | |
| SCHEMBL21057907 | 0.76 | TDP1 (0.40) | ALDH1A1TDP1LMNA | |
| SCHEMBL21104519 | 0.76 | TDP1 (0.40) | ALDH1A1TDP1LMNA | |
| SCHEMBL21138531 | 0.76 | TDP1 (0.40) | ALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197724-A1 | 6.5 -PYRROLOPIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS | BAO JIANMING | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197724-A1 | 6.5 -PYRROLOPIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS | TACR1, TACR2, HTR1D | SLC6A3 292/4885RECQL 2413/4885SLC6A4 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.