Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 15/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62571 | 0.81 | KMT2A (0.39) | APPMAPTINSR | |
| SCHEMBL62350 | 0.78 | MAOA (0.37) | APPMAPTINSRMAOAMAOB | |
| SCHEMBL62023 | 0.77 | SLC16A3 (0.38) | APPMAPTINSRMAOA | |
| SCHEMBL13931380 | 0.77 | EGFR (0.38) | APPMAPTINSRMAOA | |
| SCHEMBL13201658 | 0.77 | MAOA (0.37) | APPMAPTINSRMAOAMAOB | |
| SCHEMBL62625 | 0.76 | MAOA (0.37) | APPMAPTINSRMAOAMAOB | |
| SCHEMBL23533647 | 0.66 | SLC16A3 (0.40) | MAPTMAOA | |
| SCHEMBL11136666 | 0.64 | INSR (0.51) | APPMAPTINSR | |
| SCHEMBL11136663 | 0.64 | INSR (0.51) | APPMAPTINSR | |
| SCHEMBL31722935 | 0.62 | SLC16A3 (0.36) | MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767821-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2010-08-03 | — | — | US | disclosed |
| US-20100167417-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | BECTON, DICKINSON AND COMPANY (US) | 2010-07-01 | — | — | US | disclosed |
| US-7563891-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2009-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167417-A1 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES | NUCB2, NDC1, NCBP1 | APP 4640/4885MAPT 2743/4885INSR 4540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.