Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 2/20 | 0.35 |
| ▸ | ATP4B | P51164 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62350 | 0.92 | MAOA (0.37) | MAOASLC16A3ATP4AATP4BMAOB | |
| SCHEMBL62625 | 0.92 | MAOA (0.37) | MAOASLC16A3ATP4AATP4BMAOB | |
| SCHEMBL62023 | 0.85 | SLC16A3 (0.38) | MAOASLC16A3ELANEINSRMAPT | |
| SCHEMBL62571 | 0.81 | KMT2A (0.39) | INSRMAPTKMT2AGAABLM | |
| SCHEMBL13931380 | 0.79 | EGFR (0.38) | MAOASLC16A3INSRMAPTKMT2A | |
| SCHEMBL13201642 | 0.77 | APP (0.33) | MAOAMAOBINSRMAPTAPP | |
| SCHEMBL23533647 | 0.69 | SLC16A3 (0.40) | MAOASLC16A3ELANEMAPTKMT2A | |
| SCHEMBL23533635 | 0.65 | SLC16A3 (0.36) | SLC16A3MAOBELANEMAPTKMT2A | |
| SCHEMBL31722935 | 0.65 | SLC16A3 (0.36) | SLC16A3MAOBELANEMAPTKMT2A | |
| SCHEMBL11136666 | 0.65 | INSR (0.51) | ATP4AATP4BINSRMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071794-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON AND COMPANY (US) | 2011-12-06 | — | — | US | disclosed |
| US-7767821-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2010-08-03 | — | — | US | disclosed |
| US-7563891-B2 | Long wavelength thiol-reactive fluorophores | BECTON, DICKINSON & COMPANY (US) | 2009-07-21 | — | — | US | disclosed |