Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 7/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CBFB | Q13951 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2962892 | 0.85 | NPC1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL13203469 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL13203493 | 0.80 | NPC1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL13203478 | 0.80 | HDAC3 (0.43) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL13203579 | 0.79 | HDAC6 (0.55) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13203468 | 0.79 | IDO1 (0.43) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL13203529 | 0.77 | NPC1 (0.61) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL2977111 | 0.77 | GAA (0.60) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL13203487 | 0.77 | NPC1 (0.63) | ALDH1A1KDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL2977248 | 0.77 | TCF4 (0.46) | ALDH1A1KDM4EHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7777051-B2 | Asymmetric benzimidazoles and related compounds as potassium channel modulators | ICAGEN, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-7777051-B2 | Asymmetric benzimidazoles and related compounds as potassium channel modulators | ICAGEN, INC. (US) | 2010-08-17 | — | — | US | disclosed |