Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PORCN | Q9H237 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 4/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13205878 | 0.95 | PORCN (0.47) | PORCNCYP3A4CYP2D6CYP1A2CYP19A1 | |
| SCHEMBL12121490 | 0.85 | ACLY (0.44) | ACLYTP53PTPN1AKR1C3AKR1C2 | |
| SCHEMBL12121666 | 0.84 | ACLY (0.48) | ACLYTP53PTPN1AKR1C3AKR1C2 | |
| SCHEMBL12121604 | 0.84 | ACLY (0.54) | ACLYTP53PTPN1AKR1C3AKR1C2 | |
| SCHEMBL12121100 | 0.83 | CYP2D6 (0.60) | CYP3A4CYP2D6CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL2572179 | 0.82 | DHODH (0.50) | PORCNCYP3A4CYP2D6DHODHACLY | |
| SCHEMBL12121482 | 0.82 | MKNK1 (0.53) | CYP3A4CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL12117692 | 0.81 | DHODH (0.49) | PORCNCYP3A4CYP2D6DHODHACLY | |
| Hydrochloric Acid SCHEMBL1316097 | 0.81 | DHODH (0.49) | PORCNCYP3A4CYP2D6DHODHACLY | |
| SCHEMBL12121481 | 0.81 | ACLY (0.44) | DHODHACLYTP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087430-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | 富山化学工業株式会社 (JP) | 2010-08-05 | — | — | WO | disclosed |