Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13206155 | 0.92 | MAPT (0.47) | LRRK2HDAC2HDAC3MAPTTSHR | |
| SCHEMBL13206260 | 0.92 | LRRK2 (0.47) | LRRK2MAPTACLYPTPN11NPC1 | |
| SCHEMBL12121491 | 0.90 | PTPN11 (0.43) | LRRK2ACLYPTPN11TP53 | |
| SCHEMBL13206323 | 0.90 | CYP3A4 (0.49) | LRRK2MAPTACLYPTPN11CYP3A4 | |
| SCHEMBL13206147 | 0.90 | LRRK2 (0.49) | LRRK2ACLYPTPN11 | |
| SCHEMBL13206048 | 0.88 | MCHR1 (0.43) | LRRK2ACLYPTPN11 | |
| SCHEMBL13206532 | 0.87 | LMNA (0.40) | LRRK2TSHRHSD17B10ACLYPTPN11 | |
| SCHEMBL12121481 | 0.86 | ACLY (0.44) | HDAC2HDAC3MAPTACLYPTPN11 | |
| SCHEMBL13206064 | 0.86 | RAB9A (0.51) | ACLYMAPK1NPC1RAB9APOLB | |
| SCHEMBL13206303 | 0.86 | RAB9A (0.46) | ACLYPTPN11MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087430-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | 富山化学工業株式会社 (JP) | 2010-08-05 | — | — | WO | disclosed |