Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600146 | 0.84 | TP53 (0.48) | CALM1EPHX2CES2CES1AKR1B1 | |
| SCHEMBL9122338 | 0.80 | TP53 (0.43) | CALM1EPHX2CES2CES1AKR1B1 | |
| SCHEMBL10755368 | 0.80 | TSHR (0.43) | CALM1EPHX2CES2CES1AKR1B1 | |
| SCHEMBL29227590 | 0.80 | MAOB (0.42) | CALM1EPHX2CES2CES1AKR1B1 | |
| SCHEMBL4878935 | 0.80 | CES2 (0.44) | CALM1EPHX2CES2CES1AKR1B1 | |
| SCHEMBL28400181 | 0.79 | CALM1 (0.45) | CALM1EPHX2CES2CES1AKR1B1 | |
| SCHEMBL28443365 | 0.78 | TSHR (0.40) | CALM1EPHX2CES2CES1AKR1B1 | |
| SCHEMBL777239 | 0.78 | CES1 (0.41) | CALM1EPHX2CES2CES1AKR1B1 | |
| SCHEMBL196203 | 0.78 | CALM1 (0.50) | CALM1EPHX2TSHRALDH1A1LOXL2 | |
| SCHEMBL9123656 | 0.77 | SMN1; SMN2 (0.44) | EPHX2TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 688 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118996447-A | Phosphine-oxide substituted quinoxaline quinazolinone compound, preparation method and application thereof | 南阳师范学院 | 2024-11-22 | — | — | CN | claimed |
| CN-114181250-A | Alkenyl phosphine compound and preparation method thereof | 中国石油化工股份有限公司 | 2022-03-15 | — | — | CN | claimed |
| EP-2481760-B1 | INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME | CHINA PETROLEUM & CHEM CORP (CN) | 2021-05-05 | — | — | EP | claimed |
| CN-112500441-A | Preparation process of high-purity glycosyl phosphate | 上海彩迩文生化科技有限公司 | 2021-03-16 | — | — | CN | claimed |
| US-9382334-B2 | Optical film | SK INNOVATION CO., LTD. (KR) | 2016-07-05 | — | — | US | claimed |
| CN-103910758-B | The preparation method of a kind of axial chirality dibenzyl phosphine oxide and axial chirality dibenzyl phosphine | SUN YAT-SEN UNIVERSITY (CN) | 2016-01-20 | — | — | CN | claimed |
| US-20150004333-A1 | Optical Film | SK INNOVATION CO., LTD. (KR) | 2015-01-01 | — | — | US | claimed |
| EP-2800779-A1 | OPTICAL FILM | SK Innovation Co., Ltd. (KR) | 2014-11-12 | — | — | EP | claimed |
| CN-103910758-A | Preparation method of axially chiral biaryl phosphine oxide and axially chiral biaryl phosphine | UNIV SUN YAT SEN | 2014-07-09 | — | — | CN | claimed |
| CN-102532368-B | Rare earth catalyst and method for polymerizing conjugated diene by using same | UNIV BEIJING CHEMICAL | 2014-04-02 | — | — | CN | claimed |
| CN-103073578-A | Dibenzyl phosphinic acid synthetic method | UNIV TSINGHUA | 2013-05-01 | — | — | CN | claimed |
| CN-102532368-A | Rare earth catalyst and method for polymerizing conjugated diene by using same | UNIV BEIJING CHEMICAL | 2012-07-04 | — | — | CN | claimed |
| EP-1514542-B1 | Medicinal composition comprising Tacrine or Donepezil for improving brain function. | TOYAMA CHEMICAL CO LTD (JP) | 2012-02-22 | — | — | EP | claimed |
| US-6624322-B1 | Reacting ketones, primary amines and phosphorous compound, then oxidizing the aminophosphonate formed using halogen-free acids in water and solvent mixtures having buffers | ATOFINA (FR) | 2003-09-23 | — | — | US | claimed |
| EP-0387747-B1 | Process for the preparation of 1,3-substituted tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-on-4-ylidene-pentanoic ester | LONZA AG (CH) | 1995-05-17 | — | — | EP | claimed |
| EP-0270076-B1 | IMIDAZOLE DERIVATIVES AND A PROCESS FOR THEIR PREPARATION | LONZA AG (CH) | 1991-10-09 | — | — | EP | claimed |
| EP-0362634-A2 | Basic dihydropyridines, process for their preparation and their use as intermediates | BAYER AG (DE) | 1990-04-11 | — | — | EP | claimed |
| US-4650868-A | 7-deazapurine derivatives useful as antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-03-17 | — | — | US | claimed |
| EP-0000745-B1 | SALT OF AN OPTICALLY ACTIVE ISOMER OF PHENYLGLYCINE AND AN OPTICALLY ACTIVE ISOMER OF 2-AMINO BUTANOL AND PROCESS FOR ITS PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-15 | — | — | EP | claimed |
| EP-0000745-A1 | Salt of an optically active isomer of phenylglycine and an optically active isomer of 2-amino butanol and process for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-02-21 | — | — | EP | claimed |