Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1321 | 0.79 | CALM1 (0.47) | CALM1EPHX2CES2CES1AKR1B1 | |
| SCHEMBL7602159 | 0.78 | TP53 (0.43) | CALM1EPHX2CES2CES1AKR1B1 | |
| SCHEMBL196203 | 0.75 | CALM1 (0.50) | CALM1EPHX2TSHRALDH1A1LOXL2 | |
| SCHEMBL4331683 | 0.73 | CALM1 (0.47) | CALM1EPHX2TSHRALDH1A1LOXL2 | |
| SCHEMBL18408878 | 0.73 | CALM1 (0.47) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| Hydrochloric Acid SCHEMBL11571570 | 0.73 | CALM1 (0.47) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| Hydrochloric Acid SCHEMBL11804664 | 0.73 | CALM1 (0.47) | CALM1TSHRALDH1A1LOXL2IDO1 | |
| SCHEMBL11678015 | 0.73 | CALM1 (0.47) | CALM1EPHX2TSHRALDH1A1LOXL2 | |
| SCHEMBL18425558 | 0.73 | CALM1 (0.47) | CALM1EPHX2TSHRALDH1A1LOXL2 | |
| SCHEMBL11884686 | 0.73 | CALM1 (0.47) | CALM1EPHX2TSHRALDH1A1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111187298-B | C2-phosphono methylene indole compound and preparation method and application thereof | 成都大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-111187298-A | C2-phosphono methylene indole compound and preparation method and application thereof | 成都大学 | 2020-05-22 | — | — | CN | disclosed |