Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119664 | 0.89 | TSHR (0.56) | TSHRCA12CA14CA2CA7 | |
| SCHEMBL13762658 | 0.89 | TSHR (0.56) | TSHRCA12CA14CA2CA7 | |
| SCHEMBL13762659 | 0.89 | TSHR (0.56) | TSHRCA12CA14CA2CA7 | |
| SCHEMBL1403320 | 0.87 | TSHR (0.54) | TSHRCA12CA14CA2CA7 | |
| SCHEMBL1403311 | 0.87 | TSHR (0.54) | TSHRCA12CA14CA2CA7 | |
| SCHEMBL17188351 | 0.87 | TSHR (0.58) | TSHRCA12CA14CA2CA7 | |
| SCHEMBL2586098 | 0.87 | TSHR (0.64) | TSHRCA12CA14CA2CA7 | |
| SCHEMBL20283628 | 0.87 | TSHR (0.64) | TSHRCA12CA14CA2CA7 | |
| SCHEMBL16730520 | 0.87 | TSHR (0.64) | TSHRCA12CA14CA2CA7 | |
| SCHEMBL8214934 | 0.87 | TSHR (0.64) | TSHRCA12CA14CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393805-B1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | BIOTIUM INC (US) | 2015-08-26 | — | — | EP | disclosed |
| US-9006437-B2 | Xanthene dyes comprising a sulfonamide group | BIOTIUM, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-9006437-B2 | Xanthene dyes comprising a sulfonamide group | BIOTIUM, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20140011208-A1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | BIOTIUM, INC. | 2014-01-09 | — | — | US | disclosed |
| US-20140011208-A1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | BIOTIUM, INC. | 2014-01-09 | — | — | US | disclosed |
| US-8436170-B2 | Xanthene dyes comprising a sulfonamide group | BIOTIUM, INC. (US) | 2013-05-07 | — | — | US | disclosed |
| US-20100197030-A1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | BIOTIUM, INC. (US) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197030-A1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | XDH, ARSA, STS | TSHR 3159/4885CA12 77/4885CA14 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.