SCHEMBL13213541

SCHEMBL13213541

C=CC(=O)Oc1ccc(N(c2ccccc2)c2ccc(C=Cc3ccc(C=Cc4ccc(N(c5ccccc5)c5ccccc5)cc4)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.48
THRB P10828 3/20 0.45
RAD51 Q06609 1/20 0.44
TRPM8 Q7Z2W7 3/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
TTR P02766 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PPARA Q07869 1/20 0.39
RELA Q04206 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2609797 1.00 KMT2A (0.48) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL13337921 1.00 KMT2A (0.48) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL10102850 1.00 KMT2A (0.48) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL13818602 1.00 KMT2A (0.48) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL10102836 1.00 KMT2A (0.48) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL10102830 0.96 KMT2A (0.44) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL13909549 0.96 KMT2A (0.44) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL2609792 0.94 KMT2A (0.43) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL13431735 0.94 THRB (0.50) KMT2ATHRBRAD51CTDSP1KDM4E
SCHEMBL12234247 0.94 THRB (0.50) KMT2ATHRBRAD51CTDSP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100209842-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR YANAGAWA YOSHIKI 2010-08-19 US disclosed
US-20100209842-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR YANAGAWA YOSHIKI 2010-08-19 US disclosed
US-7718335-B2 Image bearing member, and image forming apparatus and process cartridge using the same RICOH COMPANY LIMITED (JP) 2010-05-18 US disclosed
US-7718335-B2 Image bearing member, and image forming apparatus and process cartridge using the same RICOH COMPANY LIMITED (JP) 2010-05-18 US disclosed
US-20070031746-A1 Electrophotographic photoconductor, process cartridge, and image forming method RICOH COMPANY, LTD. (JP) 2007-02-08 US disclosed
US-20070031746-A1 Electrophotographic photoconductor, process cartridge, and image forming method RICOH COMPANY, LTD. (JP) 2007-02-08 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed