SCHEMBL10102830

SCHEMBL10102830

C=CC(=O)Oc1ccc(Oc2ccc(C=Cc3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.44
SRD5A2 P31213 1/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
RAB9A P51151 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
THRB P10828 2/20 0.42
TGM2 P21980 1/20 0.41
RAD51 Q06609 1/20 0.41
TRPM8 Q7Z2W7 3/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
TLR4 O00206 1/20 0.39
TLR2 O60603 1/20 0.39
APP P05067 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13337921 0.96 KMT2A (0.48) KMT2AMEN1LMNAL3MBTL1THRB
SCHEMBL13213541 0.96 KMT2A (0.48) KMT2AMEN1LMNAL3MBTL1THRB
SCHEMBL10102836 0.96 KMT2A (0.48) KMT2AMEN1LMNAL3MBTL1THRB
SCHEMBL13818602 0.96 KMT2A (0.48) KMT2AMEN1LMNAL3MBTL1THRB
SCHEMBL10102850 0.96 KMT2A (0.48) KMT2AMEN1LMNAL3MBTL1THRB
SCHEMBL2609797 0.96 KMT2A (0.48) KMT2AMEN1LMNAL3MBTL1THRB
SCHEMBL9915750 0.93 THRB (0.47) SRD5A2NPC1ALDH1A1RAB9AL3MBTL1
SCHEMBL13909549 0.92 KMT2A (0.44) KMT2AL3MBTL1THRBRAD51TRPM8
SCHEMBL4402214 0.91 TGM2 (0.49) SRD5A2NPC1ALDH1A1RAB9AL3MBTL1
SCHEMBL2609792 0.90 KMT2A (0.43) KMT2AMEN1LMNATHRBRAD51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148038-B2 Image bearing member, process cartridge, image forming apparatus and method of forming image bearing member RICOH COMPANY, LTD. (JP) 2012-04-03 US disclosed
US-8148038-B2 Image bearing member, process cartridge, image forming apparatus and method of forming image bearing member RICOH COMPANY, LTD. (JP) 2012-04-03 US disclosed
US-20100209842-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR YANAGAWA YOSHIKI 2010-08-19 US disclosed
US-20100209842-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PREPARING THE PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE THEREFOR USING THE PHOTORECEPTOR YANAGAWA YOSHIKI 2010-08-19 US disclosed
US-20090148180-A1 IMAGE BEARING MEMBER, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS AND METHOD OF FORMING IMAGE BEARING MEMBER RICOH COMPANY, LTD. (JP) 2009-06-11 US disclosed
US-20070031746-A1 Electrophotographic photoconductor, process cartridge, and image forming method RICOH COMPANY, LTD. (JP) 2007-02-08 US disclosed
US-20070031746-A1 Electrophotographic photoconductor, process cartridge, and image forming method RICOH COMPANY, LTD. (JP) 2007-02-08 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed