SCHEMBL10102836

SCHEMBL10102836

C=CC(=O)Oc1ccc(/C=C/c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.48
THRB P10828 3/20 0.45
RAD51 Q06609 1/20 0.44
TRPM8 Q7Z2W7 3/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
TTR P02766 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PPARA Q07869 1/20 0.39
RELA Q04206 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2609797 1.00 KMT2A (0.48) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL13337921 1.00 KMT2A (0.48) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL10102850 1.00 KMT2A (0.48) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL13818602 1.00 KMT2A (0.48) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL13213541 1.00 KMT2A (0.48) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL10102830 0.96 KMT2A (0.44) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL13909549 0.96 KMT2A (0.44) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL2609792 0.94 KMT2A (0.43) KMT2ATHRBRAD51TRPM8CTDSP1
SCHEMBL13431735 0.94 THRB (0.50) KMT2ATHRBRAD51CTDSP1KDM4E
SCHEMBL12234247 0.94 THRB (0.50) KMT2ATHRBRAD51CTDSP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11754901-B2 Electrochromic device, wearable device, and method for driving electrochromic device RICOH COMPANY, LTD. (JP) 2023-09-12 US disclosed
US-11209713-B2 Electrochromic element and electrochromic dimming element RICOH COMPANY, LTD. (JP) 2021-12-28 US disclosed
US-20210032531-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2021-02-04 US disclosed
US-10634970-B2 Electrochromic element RICOH COMPANY, LTD. (JP) 2020-04-28 US disclosed
US-20200103718-A1 ELECTROCHROMIC DISPLAY DEVICE AND PRODUCTION METHOD OF ELECTROCHROMIC DISPLAY DEVICE RICOH COMPANY, LTD. (JP) 2020-04-02 US disclosed
EP-3177963-B1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH CO LTD (JP) 2020-02-19 EP disclosed
US-10429710-B2 Electrochromic device RICOH COMPANY, LTD. (JP) 2019-10-01 US disclosed
US-20190285960-A1 ELECTROCHROMIC DEVICE, ELECTRONIC DIMMING EYEGLASSES, AUGMENTED REALITY EYEGLASSES, AND CAMERA RICOH COMPANY, LTD. (JP) 2019-09-19 US disclosed
US-10409129-B2 Electrochromic element RICOH COMPANY, LTD. (JP) 2019-09-10 US disclosed
US-20170329199-A1 ELECTROCHROMIC DEVICE RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170329198-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170329198-A1 ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170329199-A1 ELECTROCHROMIC DEVICE RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-17 US disclosed
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-17 US disclosed
WO-2016021129-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2016-02-11 WO disclosed
US-8148038-B2 Image bearing member, process cartridge, image forming apparatus and method of forming image bearing member RICOH COMPANY, LTD. (JP) 2012-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210032531-A1 ELECTROCHROMIC ELEMENT TMEM109, DSG1, GPX1 KMT2A 2162/4885THRB 4504/4885RAD51 1715/4885
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT TET2, TET1, TET3 KMT2A 138/4885THRB 658/4885RAD51 4391/4885
US-11209713-B2 Electrochromic element and electrochromic dimming element TET2, TET1, TET3 KMT2A 138/4885THRB 658/4885RAD51 4391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.