SCHEMBL1322341

SCHEMBL1322341

C=C(C)C(=O)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(C)(F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
TSHR P16473 3/20 0.40
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL711200 1.00 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL712017 1.00 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL17603219 0.96 THRB (0.38) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL712811 0.95 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL30360194 0.92 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2462841 0.90 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1415453 0.90 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1536991 0.90 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL476532 0.90 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1536824 0.90 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1543074-B1 UV-CURABLE RESIN COMPOSITION FOR CLADDING OPTICAL FIBER SSCP CO LTD (KR) 2008-02-27 EP claimed
US-7046904-B2 UV-curable resin composition for cladding optical fiber SSCP CO., LTD. (KR) 2006-05-16 US claimed
US-20060067638-A1 Uv-curable resin composition for cladding optical fiber LUVANTIX CO., LTD. (KR) 2006-03-30 US claimed
EP-1543074-A4 UV-CURABLE RESIN COMPOSITION FOR CLADDING OPTICAL FIBER SSCP CO LTD (KR) 2006-01-04 EP claimed
EP-1543074-A1 UV-CURABLE RESIN COMPOSITION FOR CLADDING OPTICAL FIBER SSCP Co., Ltd. (KR) 2005-06-22 EP claimed
WO-2004024814-A1 UV-CURABLE RESIN COMPOSITION FOR CLADDING OPTICAL FIBER SSCP CO., LTD. (KR) 2004-03-25 WO claimed
EP-3004050-B1 CYANOSTILBENES ROLIC TECH AG (CH) 2020-09-02 EP disclosed
US-10329486-B2 Cyanostilbenes ROLIC AG (CH) 2019-06-25 US disclosed
EP-3004050-A1 CYANOSTILBENES Rolic AG (CH) 2016-04-13 EP disclosed
US-20160083655-A1 CYANOSTILBENES ROLIC AG (CH) 2016-03-24 US disclosed
WO-2014191292-A1 CYANOSTILBENES ROLIC AG (CH) 2014-12-04 WO disclosed
US-8778489-B2 Optical layered product TOMOEGAWA CO., LTD. (JP) 2014-07-15 US disclosed
EP-1996661-B1 FOULING RELEASE COMPOSITION JOTUN AS (NO) 2014-05-14 EP disclosed
US-6261665-B1 TRANSPARENT SUBSTRATE, PHOTOPOLYMERIZABLE SURFACE ROUGHNESS LAYER TOMOEGAWA PAPER CO., LTD. (JP) 2001-07-17 US disclosed
US-6074698-A CONTACTING A TREATMENT LIQUID CONTAINING A MONOMER HAVING A DOUBLE BOND, A POLYMERIZATION INITIATOR AND A SOLVENT WITH A RUBBER BASE MATERIAL; AND HEATING SO THAT THE MONOMER IS POLYMERIZED NIPPON VALDUA INDUSTRIES, LTD. (JP) 2000-06-13 US disclosed
EP-0890601-A1 PROCESS FOR PRODUCING SURFACE-MODIFIED RUBBER, SURFACE-MODIFIED RUBBER, AND SEALING MATERIAL NIPPON VALQUA INDUSTRIES, LTD. (JP) 1999-01-13 EP disclosed
EP-0581168-B1 Hydrophobic porous membranes, process for the manufacture thereof and their use MITSUBISHI RAYON CO (JP) 1996-10-02 EP disclosed
US-5403483-A Physically contacting fluorinated side chain methacrylated/ acrylated or crosslinked polymer with the surface of porous polyolefin membrane, heat treatment to crystallize side chain MITSUBISHI RAYON CO., LTD. (JP) 1995-04-04 US disclosed
EP-0632059-A2 Interpenetrating networks from unsaturated monomers and thermosetting resins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-04 EP disclosed
EP-0581168-A1 Hydrophobic porous membranes, process for the manufacture thereof and their use MITSUBISHI RAYON CO., LTD. (JP) 1994-02-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160083655-A1 CYANOSTILBENES LATS1, LATS2, CRY1 THRB 4281/4885TSHR 4718/4885ALDH1A1 2838/4885
US-10329486-B2 Cyanostilbenes LATS1, LATS2, CRY1 THRB 4281/4885TSHR 4718/4885ALDH1A1 2838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.