SCHEMBL712811

SCHEMBL712811

C=C(C)C(=O)OCCC(F)(F)C(F)(F)C(C)(F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.42
TSHR P16473 3/20 0.41
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL712017 0.95 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL711200 0.95 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1322341 0.95 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL17603219 0.94 THRB (0.38) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL1536985 0.88 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3843423 0.88 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL5070641 0.87 TSHR (0.38) THRBTSHR
SCHEMBL156101 0.87 THRB (0.44) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL30360194 0.86 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL476532 0.85 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200398289-A1 ARTICLES FOR MANIPULATING IMPINGING LIQUIDS AND ASSOCIATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-12-24 US claimed
US-20190118232-A1 ARTICLES FOR MANIPULATING IMPINGING LIQUIDS AND ASSOCIATED METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2019-04-25 US claimed
US-9498934-B2 Grafted polymer surfaces for dropwise condensation, and associated methods of use and manufacture MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-11-22 US claimed
US-20160159038-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2016-06-09 US claimed
EP-2956248-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE Massachusetts Institute of Technology (US) 2015-12-23 EP claimed
US-20140314982-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-10-23 US claimed
WO-2014127304-A1 GRAFTED POLYMER SURFACES FOR DROPWISE CONDENSATION, AND ASSOCIATED METHODS OF USE AND MANUFACTURE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-08-21 WO claimed
US-7031589-B2 Material for attenuating light signals with low reflectance in a fiber optic network FURUKAWA ELECTRIC NORTH AMERICA (US) 2006-04-18 US claimed
US-20040264908-A1 Material for attenuating light signals with low reflectance in a fiber optic network FURUKAWA ELECTRIC NORTH AMERICA, INC. 2004-12-30 US claimed
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
US-11992367-B2 Acoustic-wave-probe resin material, acoustic lens, acoustic wave probe, acoustic wave determination device, ultrasound diagnostic apparatus, photo-acoustic wave determination device, ultrasonic endoscope, and method for producing acoustic lens FUJIFILM CORPORATION (JP) 2024-05-28 US disclosed
EP-3777696-B1 ACOUSTIC WAVE PROBE RESIN MATERIAL, ACOUSTIC LENS, ACOUSTIC WAVE PROBE, ACOUSTIC WAVE MEASURING APPARATUS, ULTRASONIC DIAGNOSTIC APPARATUS, PHOTOACOUSTIC WAVE MEASURING APPARATUS, ULTRASONIC ENDOSCOPE, AND METHOD FOR MANUFACTURING ACOUSTIC LENS FUJIFILM CORP (JP) 2024-02-28 EP disclosed
US-20240059860-A1 METHODS AND SYSTEMS FOR DESTRUCTION OF SYNTHETIC PER- AND POLYFLUORO COMPOUNDS CHZ TECHNOLOGIES, LLC 2024-02-22 US disclosed
WO-2024024502-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION 日産化学株式会社 2024-02-01 WO disclosed
US-20050165129-A1 Dental coating materials IVOCLAR VIVADENT AG (LI) 2005-07-28 US disclosed
US-20050026081-A1 Volume hologram recording photosensitive composition, and volume hologram recording medium using the same FUJI PHOTO FILM CO., LTD. 2005-02-03 US disclosed
US-20040264908-A1 Material for attenuating light signals with low reflectance in a fiber optic network FURUKAWA ELECTRIC NORTH AMERICA, INC. 2004-12-30 US disclosed
US-6074698-A CONTACTING A TREATMENT LIQUID CONTAINING A MONOMER HAVING A DOUBLE BOND, A POLYMERIZATION INITIATOR AND A SOLVENT WITH A RUBBER BASE MATERIAL; AND HEATING SO THAT THE MONOMER IS POLYMERIZED NIPPON VALDUA INDUSTRIES, LTD. (JP) 2000-06-13 US disclosed
EP-0890601-A1 PROCESS FOR PRODUCING SURFACE-MODIFIED RUBBER, SURFACE-MODIFIED RUBBER, AND SEALING MATERIAL NIPPON VALQUA INDUSTRIES, LTD. (JP) 1999-01-13 EP disclosed
EP-0632059-A2 Interpenetrating networks from unsaturated monomers and thermosetting resins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050165129-A1 Dental coating materials PHOSPHO1, SPTAN1, ITGA1 THRB 3247/4885TSHR 4370/4885ALDH1A1 2568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.