Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | ODC1 | P11926 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | PRKCB | P05771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17126850 | 0.86 | USP2 (0.43) | HTTCYP3A4USP2SPHK1LPAR1 | |
| SCHEMBL12582706 | 0.82 | USP2 (0.50) | HTTCYP3A4USP2SPHK1LPAR1 | |
| SCHEMBL23851234 | 0.80 | USP2 (0.53) | HTTUSP2SPHK1LPAR1LPAR3 | |
| SCHEMBL18019302 | 0.80 | USP2 (0.53) | HTTUSP2SPHK1LPAR1LPAR3 | |
| SCHEMBL18290924 | 0.80 | TSHR (0.44) | HTTCYP3A4USP2SPHK1LPAR1 | |
| SCHEMBL14262302 | 0.80 | LPAR1 (0.37) | HTTCYP3A4USP2SPHK1LPAR1 | |
| SCHEMBL28848149 | 0.80 | USP2 (0.53) | HTTUSP2SPHK1LPAR1LPAR3 | |
| SCHEMBL12201729 | 0.80 | CYP3A4 (0.55) | HTTCYP3A4USP2SPHK1ODC1 | |
| SCHEMBL14952421 | 0.79 | CYP3A4 (0.44) | ADRB2ADRB1ADRB3HTTCYP3A4 | |
| SCHEMBL12587449 | 0.79 | CYP3A4 (0.44) | ADRB2ADRB1ADRB3HTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197573-A1 | Transglutaminase Mediated Conjugation of Growth Hormone | NOVO NORDISK HEALTH CARE AG (CH) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197573-A1 | Transglutaminase Mediated Conjugation of Growth Hormone | TGM2, GHITM, GHRHR | ADRB2 4186/4885ADRB1 4107/4885ADRB3 3988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.