SCHEMBL1322700

SCHEMBL1322700

N#CCc1c(F)c(F)c(C#N)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
MAPT P10636 2/20 0.33
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 3/20 0.33
TSHR P16473 1/20 0.32
RECQL P46063 1/20 0.32
TRPV4 Q9HBA0 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24786781 0.95 MEN1 (0.31) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL24146397 0.93 MEN1 (0.31) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL24133949 0.92 MEN1 (0.32) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL24786217 0.90 MEN1 (0.31) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL24787734 0.90 MEN1 (0.31) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL24832072 0.88 MEN1 (0.31) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL24147298 0.87 KDM4E (0.35) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL24108091 0.87
SCHEMBL24108553 0.87 KDM4E (0.31) MEN1KMT2AALDH1A1KDM4ETSHR
SCHEMBL24108093 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015007729-A1 PROCESS FOR 1,2,3-TRIYLIDENETRIS(CYANOMETHANYLYLIDENE))TRIS(2,3,5,6-TETRAFLUOROBENZONITRILE)-CYCLOPROPANE NOVALED GMBH (DE) 2015-01-22 WO claimed
EP-2826768-A1 Process for manufacturing 1,2,3-triylidenetris(cyanomethanylylidene)tris(2,3,5,6-tetrafluorobenzonitrile)-cyclopropane Novaled GmbH (DE) 2015-01-21 EP claimed
EP-4635271-A1 ORGANIC ELECTROLUMINESCENT DEVICE, SEMICONDUCTING MATERIAL, SEMICONDUCTING LAYER, COMPOUND, ELECTRONIC DEVICE AND DISPLAY DEVICE Novaled GmbH (DE) 2025-10-22 EP disclosed
CN-111480245-B Light-emitting element, light-emitting device, electronic apparatus, and lighting device 株式会社半导体能源研究所 2025-06-24 CN disclosed
CN-120166858-A Light emitting device 株式会社半导体能源研究所 2025-06-17 CN disclosed
CN-120081874-A Organic compound, light-emitting device, light-emitting apparatus, electronic device, and lighting apparatus 株式会社半导体能源研究所 2025-06-03 CN disclosed
CN-120076572-A Light emitting device 株式会社半导体能源研究所 2025-05-30 CN disclosed
CN-119947404-A Light emitting device 株式会社半导体能源研究所 2025-05-06 CN disclosed
CN-119896076-A Organic electroluminescent device, semiconductor material, semiconductor layer, compound, electronic device, and display device 诺瓦尔德股份有限公司 2025-04-25 CN disclosed
CN-119894227-A Light emitting element, display device, electronic device, and lighting device 株式会社半导体能源研究所 2025-04-25 CN disclosed
CN-119856600-A Light emitting device and display apparatus 株式会社半导体能源研究所 2025-04-18 CN disclosed
US-8057712-B2 Radialene compounds and their use NOVALED AG (DE) 2011-11-15 US disclosed
EP-2180029-B1 Radialene compounds and their use NOVALED AG (DE) 2011-07-27 EP disclosed
US-7981324-B2 Oxocarbon-, pseudooxocarbon- and radialene compounds and their use NOVALED AG (DE) 2011-07-19 US disclosed
US-20100102709-A1 RADIALENE COMPOUNDS AND THEIR USE NOVALED AG (DE) 2010-04-29 US disclosed
EP-2180029-A1 Radialene compounds and their use Novaled AG (DE) 2010-04-28 EP disclosed
US-20080265216-A1 Use as doping agent for doping organic semiconductive matrix material, as blocker material, as charge injection layer, as electrode material as well as organic semiconductor, electronic component; 1,3-Bi(dicyanomethylene)indane-2-ylidene-bis(4-oxo-[3,5-di-t-butyl]-2,5-cyclohexadienylidene)cyclopropane NOVALED AG (DE) 2008-10-30 US disclosed
US-4965394-A REACTING PENTAFLUOROBENZONITRILE WITH A GRIGNARD REAGENT ICI AMERICAS INC. 1990-10-23 US disclosed
US-4866185-A HEAT RESISTANT POLYMERS; CHEMICAL INTERMEDIATES ICI AMERICAS INC. (US) 1989-09-12 US disclosed
US-4783547-A Polyfluoroaromatic nitriles ICI AMERICAS INC. (US) 1988-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100102709-A1 RADIALENE COMPOUNDS AND THEIR USE CHRNB2, CHRNB3, CHRNB4 MEN1 1668/4885KMT2A 2449/4885MAPT 2673/4885
US-20080265216-A1 Use as doping agent for doping organic semiconductive matrix material, as blocker material, as charge injection layer, as electrode material as well as organic semiconductor, electronic component; 1,3-Bi(dicyanomethylene)indane-2-ylidene-bis(4-oxo-[3,5-di-t-butyl]-2,5-cyclohexadienylidene)cyclopropane CHRNB1, GJB2, CHRNB3 MEN1 3536/4885KMT2A 3588/4885MAPT 3178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.