SCHEMBL1322720

SCHEMBL1322720

C=C(OC(C)=O)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 3/20 0.45
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL28953761 0.91 HSD17B10 (0.42) HSD17B10TDP1ALDH1A1TSHR
SCHEMBL24321872 0.78 HSD17B10 (0.41) HSD17B10TDP1
SCHEMBL112173 0.76
SCHEMBL28814142 0.76 TDP1 (0.52) HSD17B10TDP1ALDH1A1TSHR
SCHEMBL11554857 0.76
SCHEMBL28867903 0.76
SCHEMBL7261673 0.75 ALDH1A1 (0.33) HSD17B10ALDH1A1
SCHEMBL53 0.72 ALDH1A1 (0.50) HSD17B10TDP1ALDH1A1TSHR
SCHEMBL4382071 0.72 ALDH1A1 (0.50) HSD17B10TDP1ALDH1A1TSHR
Trifluoroacetic Acid SCHEMBL10398782 0.72 ALDH1A1 (0.59) HSD17B10TDP1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210332040-A1 SUBSTITUTED 4-AMINO-1H-IMIDAZO[4,5-c]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION INNATE TUMOR IMMUNITY INC (US) 2021-10-28 US claimed
US-7807300-B2 comprising an electron withdrawing group such as trifluoromethylvinyl acetate and 2,2,2-trifluoroacetamide, an aromatic diacid salt, an inorganic salt, an aliphatic organic acid, an aromatic diacid, and an aromatic monoacid; for a battery cell in an implantable medical device MEDTRONIC, INC. (US) 2010-10-05 US claimed
US-20100136426-A1 comprising an electron withdrawing group such as trifluoromethylvinyl acetate and 2,2,2-trifluoroacetamide, an aromatic diacid salt, an inorganic salt, an aliphatic organic acid, an aromatic diacid, and an aromatic monoacid; for a battery cell in an implantable medical device MEDTRONIC, INC. (US) 2010-06-03 US claimed
US-20070178378-A1 comprising an electron withdrawing group such as trifluoromethylvinyl acetate and 2,2,2-trifluoroacetamide, an aromatic diacid salt, an inorganic salt, an aliphatic organic acid, an aromatic diacid, and an aromatic monoacid; for a battery cell in an implantable medical device MEDTRONIC, INC. 2007-08-02 US claimed
EP-0592552-B1 CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES DU PONT (US) 1997-05-28 EP claimed
US-5559267-A ENANTIOMORPHS, STEREOCHEMICAL CONTROL AND ASSYMETRIC INDUCTION, HYDROGENATION OF UNSATURATED ESTERS, COORDINATION CATALYSTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-24 US claimed
EP-0592552-A1 CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES. DU PONT (US) 1994-04-20 EP claimed
WO-1993001199-A1 CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-01-21 WO claimed
JP-62108845-A None JP disclosed
WO-2025106690-A1 PRECURSOR CONCENTRATION MONITORING LAM RESEARCH CORPORATION (US) 2025-05-22 WO disclosed
CN-118668496-A Wear-resistant jean fabric and preparation method thereof 佛山市南海雄科纺织有限公司 2024-09-20 CN disclosed
CN-115101893-B Method for preparing lithium battery diaphragm by using high melt index and low melt index polypropylene 界首市天鸿新材料股份有限公司 2024-04-12 CN disclosed
US-11945890-B2 Fluorinated PVC copolymer compositions for increased ultraviolet protection Mexichem Specialty Resins Inc. (US) 2024-04-02 US disclosed
WO-2024042043-A1 A SCALABLE PROCESS FOR THE PREPARATION OF A GLYT-1 INHIBITOR BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-02-29 WO disclosed
EP-0541395-B1 Coating agents TAKEMOTO OIL & FAT CO LTD (JP) 1996-05-08 EP disclosed
US-5501904-A POLYSILOXANE-VINYL GRAFT POLYMER TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 1996-03-26 US disclosed
US-5405691-A Polysiloxane-polyvinyl graft copolymer TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 1995-04-11 US disclosed
EP-0541395-A1 Coating agents Takemoto Yushi Kabushiki Kaisha (JP) 1993-05-12 EP disclosed
JP-S62108845-A PRODUCTION OF ALPHA-PERFLUOROALKYLVINYL ESTER CENTRAL GLASS CO LTD 1987-05-20 JP disclosed
US-4149010-A Synthesis of α-trifluoromethyl vinyl acetate POLAROID CORPORATION (US) 1979-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210332040-A1 SUBSTITUTED 4-AMINO-1H-IMIDAZO[4,5-c]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION NLRP3, NOD1, NLRP1 HSD17B10 4099/4885TDP1 889/4885ALDH1A1 3065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.