Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26083144 | 0.77 | GAA (0.39) | GAAKDM4EMAPK1HTTSMN1; SMN2 | |
| SCHEMBL9816089 | 0.77 | TSHR (0.38) | ACHEGAAKDM4EMAPK1HTT | |
| SCHEMBL24239672 | 0.76 | ALDH1A1 (0.46) | ACHEGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL20355693 | 0.75 | GAA (0.49) | GAAKDM4EHTTSMN1; SMN2KMT2A | |
| SCHEMBL5697678 | 0.75 | MAPT (0.45) | GAAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL16623966 | 0.74 | KDM4E (0.39) | GAAKDM4EMAPK1EPHX1KMT2A | |
| SCHEMBL16623965 | 0.74 | EPHX1 (0.39) | GAAKDM4EEPHX1KMT2ATSHR | |
| SCHEMBL22111948 | 0.71 | GAA (0.56) | ACHEGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL17740426 | 0.71 | EPHX2 (0.34) | GAAKDM4EHTTEPHX1NAAA | |
| SCHEMBL10719486 | 0.70 | GAA (0.54) | ACHEGAAMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772325-B2 | Thermoplastic elastomer composition | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |