Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16623965 | 0.82 | EPHX1 (0.39) | KDM4EGAAKMT2ATSHREPHX1 | |
| SCHEMBL16623954 | 0.80 | KDM4E (0.39) | KDM4EGAAKMT2ATSHREPHX1 | |
| SCHEMBL1050026 | 0.78 | GAA (0.47) | KDM4EGAAKMT2ATSHRMAPK8 | |
| SCHEMBL13227481 | 0.74 | ACHE (0.42) | KDM4EGAAKMT2ATSHREPHX1 | |
| SCHEMBL26083144 | 0.73 | GAA (0.39) | KDM4EGAAKMT2ATSHREPHX1 | |
| SCHEMBL16623953 | 0.72 | KDM4E (0.41) | KDM4EGAAKMT2ATSHREPHX1 | |
| SCHEMBL16623952 | 0.72 | GAA (0.35) | GAAKMT2ATSHREPHX1ALDH1A1 | |
| SCHEMBL20355693 | 0.71 | GAA (0.49) | KDM4EGAAKMT2ATSHRMAPK8 | |
| Hydrochloric Acid SCHEMBL6558032 | 0.70 | ALDH1A1 (0.37) | KDM4EGAAKMT2ATSHRZDHHC20 | |
| SCHEMBL16626782 | 0.69 | TSHR (0.34) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10780026-B2 | Methods of forming dental composites and compositions for reduced shrinkage stress | DENTSPLY SIRONA INC. (US) | 2020-09-22 | — | — | US | disclosed |
| EP-3052481-B1 | USE OF POLYMERIZABLE STABLE RADICALS FOR REDUCING THE SHRINKAGE STRESS OF DENTAL COMPOSITIONS | DENTSPLY SIRONA INC (US) | 2020-04-08 | — | — | EP | disclosed |
| US-20190224081-A1 | METHODS OF FORMING DENTAL COMPOSITES AND COMPOSITIONS FOR REDUCED SHRINKAGE STRESS | DENTSPLY SIRONA INC (US) | 2019-07-25 | — | — | US | disclosed |
| US-20150099821-A1 | DENTAL COMPOSITE COMPOSITIONS FOR REDUCED STRESS SHRINKAGE | DENTSPLY SIRONA INC. | 2015-04-09 | — | — | US | disclosed |
| WO-2015051217-A1 | DENTAL COMPOSITE COMPOSITIONS FOR REDUCED STRESS SHRINKAGE | DENTSPLY INTERNATIONAL INC. (US) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099821-A1 | DENTAL COMPOSITE COMPOSITIONS FOR REDUCED STRESS SHRINKAGE | VCL, HSPA4L, GPX4 | KDM4E 998/4885GAA 3472/4885KMT2A 3260/4885 |
| US-10780026-B2 | Methods of forming dental composites and compositions for reduced shrinkage stress | SMCHD1, FHIT, ACR | KDM4E 1577/4885GAA 2587/4885KMT2A 2852/4885 |
| US-20190224081-A1 | METHODS OF FORMING DENTAL COMPOSITES AND COMPOSITIONS FOR REDUCED SHRINKAGE STRESS | SMCHD1, FHIT, ACR | KDM4E 1577/4885GAA 2587/4885KMT2A 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.