SCHEMBL1322903

SCHEMBL1322903

O=[Si]([O-])[O-].O=[Si]([O-])[O-].O=[Si]([O-])[O-].[Ca+2].[Mg+2].[Sr+2]

nearest known ligand 0.00

Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL743249 0.94
SCHEMBL7253675 0.94
SCHEMBL29215 0.94
SCHEMBL7156868 0.89
Zinc Ion SCHEMBL987037 0.89
Water SCHEMBL16223174 0.89
SCHEMBL3239359 0.89
Water SCHEMBL6243762 0.89
SCHEMBL216770 0.89
SCHEMBL5877736 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8057568-B2 Enables substrate porosities of about 60% to 90%; substrate for a filter or catalyst host, or catalytic converter; high permeability GEO2 TECHNOLOGIES, INC. (US) 2011-11-15 US claimed
EP-2516036-A2 FIBER ENHANCED POROUS SUBSTRATE GEO2 Technologies, Inc. (US) 2012-10-31 EP disclosed
WO-2011084688-A2 FIBER ENHANCED POROUS SUBSTRATE GEO2 TECHNOLOGIES, INC (US) 2011-07-14 WO disclosed
US-20110151181-A1 Fiber Enhanced Porous Substrate GEO2 TECHNOLOGIES, INC. (US) 2011-06-23 US disclosed
US-7938876-B2 Compositional structure of RxMg2Al4+2xSi5-xO18 or RxMg2-xAl4Si5O18; heat treatment; filter; catalytic converter GE02 Technologies, Inc. (US) 2011-05-10 US disclosed
EP-2265558-A2 LOW COEFFICIENT OF THERMAL EXPANSION MATERIALS INCLUDING NONSTOICHIOMETRIC CORDIERITE FIBERS AND METHODS OF MANUFACTURE GEO2 Technologies, Inc. (US) 2010-12-29 EP disclosed
US-7855163-B2 Low coefficient of thermal expansion bonding system for a high porosity ceramic body and methods of manufacture GEO2 TECHNOLOGIES, INC. (US) 2010-12-21 US disclosed
EP-2152492-A2 LOW COEFFICIENT OF THERMAL EXPANSION BONDING SYSTEM FOR A HIGH POROSITY CERAMIC BODY AND METHODS OF MANUFACTURE GEO2 Technologies, Inc. (US) 2010-02-17 EP disclosed
WO-2009129152-A2 LOW COEFFICIENT OF THERMAL EXPANSION MATERIALS INCLUDING NONSTOICHIOMETRIC CORDIERITE FIBERS AND METHODS OF MANUFACTURE GEO2 TECHNOLOGIES, INC. (US) 2009-10-22 WO disclosed
WO-2008144291-A2 LOW COEFFICIENT OF THERMAL EXPANSION BONDING SYSTEM FOR A HIGH POROSITY CERAMIC BODY AND METHODS OF MANUFACTURE GEO2 TECHNOLOGIES, INC. (US) 2008-11-27 WO disclosed
US-20080283465-A1 LOW COEFFICIENT OF THERMAL EXPANSION BONDING SYSTEM FOR A HIGH POROSITY CERAMIC BODY AND METHODS OF MANUFACTURE GEO2 TECHNOLOGIES, INC. (US) 2008-11-20 US disclosed
US-20080242530-A1 Low coefficient of thermal expansion materials including nonstoichiometric cordierite fibers and methods of manufacture GEO2 TECHNOLOGIES, INC. (US) 2008-10-02 US disclosed
WO-2008094954-A1 A POROUS SUBSTRATE AND METHOD OF FABRICATING THE SAME GEO2 TECHNOLOGIES, INC. (US) 2008-08-07 WO disclosed
US-20080178992-A1 Porous Substrate and Method of Fabricating the Same GEO2 TECHNOLOGIES, INC. (US) 2008-07-31 US disclosed
US-3732416-A DISCLOSING LIGHT GTE SYLVANIA INC 1973-05-08 US disclosed