Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | MC4R | P32245 | 1/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.65 |
| ▸ | MC3R | P41968 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4627976 | 0.86 | ADRB2 (0.71) | ADRB2TSHRHIF1AADRA1ACYP3A4 | |
| Metaproterenol SCHEMBL3694829 | 0.83 | ADRB2 (1.00) | ADRB2TSHRHIF1AADRA1ACYP3A4 | |
| Metaproterenol SCHEMBL4451598 | 0.83 | ADRB2 (1.00) | ADRB2TSHRHIF1AADRA1ACYP3A4 | |
| Metaproterenol SCHEMBL4270 | 0.83 | ADRB2 (1.00) | ADRB2TSHRHIF1AADRA1ACYP3A4 | |
| Metaproterenol SCHEMBL4271 | 0.83 | ADRB2 (1.00) | ADRB2TSHRHIF1AADRA1ACYP3A4 | |
| SCHEMBL2488461 | 0.82 | ADRB2 (1.00) | ADRB2TSHRHIF1AADRA1ACYP3A4 | |
| SCHEMBL29854020 | 0.82 | ADRB2 (1.00) | ADRB2TSHRHIF1AADRA1ACYP3A4 | |
| SCHEMBL2488460 | 0.82 | ADRB2 (1.00) | ADRB2TSHRHIF1AADRA1ACYP3A4 | |
| SCHEMBL19329750 | 0.82 | ADRB2 (0.67) | ADRB2TSHRHIF1AADRA1ACYP3A4 | |
| Metaproterenol SCHEMBL6141868 | 0.81 | ADRB2 (0.96) | ADRB2TSHRHIF1AADRA1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168245-A1 | PREPARATION OF (R,R)-FENOTEROL AND (R,R)-OR (R,S)-FENOTEROL ANALOGUES AND THEIR USE IN TREATING CONGESTIVE HEART FAILURE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168245-A1 | PREPARATION OF (R,R)-FENOTEROL AND (R,R)-OR (R,S)-FENOTEROL ANALOGUES AND THEIR USE IN TREATING CONGESTIVE HEART FAILURE | ADRB2, ADRB1, ADRB3 | ADRB2 1/4885TSHR 89/4885HIF1A 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.