Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13232197 | 0.82 | LMNA (0.35) | LMNAHTTNPSR1SMN1; SMN2GPR55 | |
| SCHEMBL3029212 | 0.72 | HTT (0.32) | LMNAHTTNPSR1SMN1; SMN2TDP1 | |
| SCHEMBL3029213 | 0.72 | HTT (0.32) | LMNAHTTNPSR1SMN1; SMN2TDP1 | |
| SCHEMBL3023619 | 0.70 | HTT (0.34) | LMNAHTTNPSR1SMN1; SMN2GPR55 | |
| SCHEMBL3023623 | 0.70 | HTT (0.34) | LMNAHTTNPSR1SMN1; SMN2GPR55 | |
| SCHEMBL3017250 | 0.67 | XDH (0.46) | LMNAHTTNPSR1SMN1; SMN2GPR55 | |
| SCHEMBL2166817 | 0.67 | XDH (0.46) | LMNAHTTNPSR1SMN1; SMN2GPR55 | |
| SCHEMBL3017249 | 0.67 | XDH (0.46) | LMNAHTTNPSR1SMN1; SMN2GPR55 | |
| SCHEMBL3031993 | 0.67 | GFER (0.33) | LMNAHTTNPSR1SMN1; SMN2TDP1 | |
| SCHEMBL3026110 | 0.65 | HTT (0.34) | LMNAHTTNPSR1SMN1; SMN2GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100167933-A1 | Piperazine Compounds With Herbicidal Action | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100167933-A1 | Piperazine Compounds With Herbicidal Action | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| WO-2009000757-A1 | PIPERAZINE COMPOUNDS WITH HERBICIDAL ACTION | BASF SE (DE) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167933-A1 | Piperazine Compounds With Herbicidal Action | PRXL2A, CBR1, CBR3 | LMNA 4628/4885HTT 2679/4885NPSR1 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.