Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.95 |
| ▸ | PTPN12 | Q05209 | 4/20 | 0.95 |
| ▸ | PTPN22 | Q9Y2R2 | 4/20 | 0.95 |
| ▸ | GUSB | P08236 | 2/20 | 0.85 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PNLIP | P16233 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Kumanon H SCHEMBL13233442 | 0.97 | PTPN1 (1.00) | PTPN1PTPN12PTPN22GUSBHIF1A | |
| Kumanon H SCHEMBL27014815 | 0.97 | PTPN1 (1.00) | PTPN1PTPN12PTPN22GUSBHIF1A | |
| Kumanon H SCHEMBL29541171 | 0.97 | PTPN1 (1.00) | PTPN1PTPN12PTPN22GUSBHIF1A | |
| Kumanon H SCHEMBL30912100 | 0.97 | PTPN1 (1.00) | PTPN1PTPN12PTPN22GUSBHIF1A | |
| Kumanon H SCHEMBL30318001 | 0.97 | PTPN1 (1.00) | PTPN1PTPN12PTPN22GUSBHIF1A | |
| Kumanon H SCHEMBL27013550 | 0.97 | PTPN1 (1.00) | PTPN1PTPN12PTPN22GUSBHIF1A | |
| Kumanon H SCHEMBL150578 | 0.97 | PTPN1 (1.00) | PTPN1PTPN12PTPN22GUSBHIF1A | |
| Kumanon H SCHEMBL29540653 | 0.97 | PTPN1 (1.00) | PTPN1PTPN12PTPN22GUSBHIF1A | |
| SCHEMBL20223335 | 0.95 | PTPN1 (0.95) | PTPN1PTPN12PTPN22GUSBHIF1A | |
| Kumanon G SCHEMBL20223334 | 0.92 | PTPN1 (1.00) | PTPN1PTPN12PTPN22GUSBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100166898-A1 | ANTI-BACTERIAL USE OF EXTRACT FROM MORUS AUSTRALIS POIR. AND COMPOUND KUWANON H | MEDICAL AND PHARMACEUTICAL INDUSTRY TECHNOLOGY AND DEVELOPMENT CENTER (TW) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100166898-A1 | ANTI-BACTERIAL USE OF EXTRACT FROM MORUS AUSTRALIS POIR. AND COMPOUND KUWANON H | SPOUT1, HK1, KCNH1 | PTPN1 3456/4885PTPN12 2763/4885PTPN22 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.