Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 1/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.63 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 11/20 | 0.60 |
| ▸ | KCNK9 | Q9NPC2 | 11/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23624239 | 0.88 | GABRA2 (0.81) | GABRA2GABRB2SLC2A2 | |
| SCHEMBL30416749 | 0.87 | GABRA2 (0.63) | GABRA2GABRB2SLC2A2KCNK3KCNK9 | |
| SCHEMBL30417903 | 0.80 | KCNK3 (0.58) | GABRA2GABRB2SLC2A2KCNK3KCNK9 | |
| SCHEMBL8208 | 0.80 | KDM4E (0.64) | GABRB2SLC2A2KCNK3KCNK9KDM4E | |
| SCHEMBL7231287 | 0.79 | KCNK3 (0.65) | KCNK3KCNK9KDM4E | |
| SCHEMBL22364213 | 0.78 | KCNK3 (0.76) | KCNK3KCNK9KDM4E | |
| SCHEMBL23624075 | 0.78 | GABRB2 (0.63) | GABRA2GABRB2SLC2A2KCNK3KCNK9 | |
| SCHEMBL6669200 | 0.77 | SLC2A2 (0.62) | SLC2A2KCNK3KCNK9KDM4ERAB9A | |
| SCHEMBL1430614 | 0.76 | SLC2A2 (0.77) | GABRB2SLC2A2KCNK3KCNK9KDM4E | |
| SCHEMBL1431027 | 0.76 | KDM4E (0.59) | GABRB2KCNK3KCNK9KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460592-A | HYPNOTIC | SYNTHELABO | 1984-07-17 | — | — | US | disclosed |
| US-4382938-A | HYPNOSIS; TENSION; ANTICONVULSANTS; PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | SYNTHELABO (FR) | 1983-05-10 | — | — | US | disclosed |