Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12119952 | 0.87 | GFER (0.45) | GFERALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL13605948 | 0.80 | GFER (0.45) | GFERALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL12119951 | 0.77 | GFER (0.52) | GFERALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL8163011 | 0.76 | GFER (0.43) | GFERALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL8163013 | 0.76 | GFER (0.46) | GFERALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL6340781 | 0.75 | GFER (0.55) | GFERALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL7636534 | 0.75 | ALDH1A1 (0.48) | GFERALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL7630261 | 0.74 | KMT2A (0.46) | GFERALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL3843434 | 0.74 | GAA (0.43) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL3209301 | 0.74 | GFER (0.57) | GFERALDH1A1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937689-B1 | INTERMEDIATE AND PROCESS OF PREPARATION OF ECTEINASCIDINS SUCH AS ECTEINASCIDINS 583 AND 597 USING SUCH INTERMEDIATE | CENTRE NAT RECH SCIENT (FR) | 2012-04-18 | — | — | EP | disclosed |
| US-8058435-B2 | Intermediate and process of preparation of ecteinascidin such as ecteinascidines-583,597 using such intermediate | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-11-15 | — | — | US | disclosed |
| US-8058435-B2 | Intermediate and process of preparation of ecteinascidin such as ecteinascidines-583,597 using such intermediate | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-11-15 | — | — | US | disclosed |
| US-8058435-B2 | Intermediate and process of preparation of ecteinascidin such as ecteinascidines-583,597 using such intermediate | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-11-15 | — | — | US | disclosed |
| US-20090171080-A1 | Intermediate and Process of Preparation of Ecteinascidin Such as Ecteinascidines-583,597 Using Such Intermediate | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-07-02 | — | — | US | disclosed |
| US-20090171080-A1 | Intermediate and Process of Preparation of Ecteinascidin Such as Ecteinascidines-583,597 Using Such Intermediate | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-07-02 | — | — | US | disclosed |
| US-20090171080-A1 | Intermediate and Process of Preparation of Ecteinascidin Such as Ecteinascidines-583,597 Using Such Intermediate | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-07-02 | — | — | US | disclosed |
| EP-1937689-A2 | INTERMEDIATE AND PROCESS OF PREPARATION OF ECTEINASCIDIN SUCH AS ECTEINASCIDINES-583, 597 USING SUCH INTERMEDIATE | Centre National de la Recherche Scientifique (FR) | 2008-07-02 | — | — | EP | disclosed |
| EP-1792904-A1 | Intermediate and process of preparation of ecteinascidin using such intermediate | Centre National de la Recherche Scientifique (CNRS) (FR) | 2007-06-06 | — | — | EP | disclosed |
| WO-2007045686-A2 | INTERMEDIATE AND PROCESS OF PREPARATION OF ECTEINASCIDIN SUCH AS ECTEINASCIDINES-583, 597 USING SUCH INTERMEDIATE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007045686-A2 | INTERMEDIATE AND PROCESS OF PREPARATION OF ECTEINASCIDIN SUCH AS ECTEINASCIDINES-583, 597 USING SUCH INTERMEDIATE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090171080-A1 | Intermediate and Process of Preparation of Ecteinascidin Such as Ecteinascidines-583,597 Using Such Intermediate | MMP7, CCR7, AREG | GFER 3070/4885ALDH1A1 1550/4885MAPT 4680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.