Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18561767 | 1.00 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL7123845 | 0.77 | TSHR (0.50) | ALDH1A1 | |
| SCHEMBL18574411 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL22853564 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL19229748 | 0.74 | TP53 (0.32) | — | |
| SCHEMBL18561768 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL58897 | 0.73 | LMNA (0.42) | ALDH1A1 | |
| SCHEMBL14366518 | 0.73 | LMNA (0.42) | ALDH1A1 | |
| SCHEMBL18211555 | 0.72 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL109374 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170057942-A1 | ISOQUINOLINE DERIVATIVES AND USE THEREOF | PURDUE PHARMA L.P. | 2017-03-02 | — | — | US | disclosed |
| US-7763649-B2 | Carotenoid analogs or derivatives for controlling connexin 43 expression | CARDAX PHARMACEUTICALS, INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-7521584-B2 | Carotenoid analogs or derivatives for the inhibition and amelioration of disease | CARDAX PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170057942-A1 | ISOQUINOLINE DERIVATIVES AND USE THEREOF | KCNQ3, KCNQ5, KCNQ4 | ALDH1A1 550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.