SCHEMBL7123845

SCHEMBL7123845

CC(C)(C)C(O)C(O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
PGD P52209 1/20 0.45
ALDH1A1 P00352 3/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
PTGS1 P23219 1/20 0.40
CYP2C9 P11712 1/20 0.33
PDE4A P27815 1/20 0.33
SLC7A5 Q01650 1/20 0.33
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
GBA1 P04062 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13239074 0.77 ALDH1A1 (0.30) ALDH1A1
SCHEMBL18561767 0.77 ALDH1A1 (0.30) ALDH1A1
SCHEMBL18574411 0.74 ALDH1A1 (0.33) PGDALDH1A1MAPTPTGS1
SCHEMBL18211564 0.74 TP53 (0.45) TSHRPGDALDH1A1TP53MAPT
Cadaverine Tartrate SCHEMBL30041704 0.74 TSHR (0.56) TSHRPGDALDH1A1TP53MAPT
SCHEMBL25004681 0.74 TSHR (0.47) TSHRPGDALDH1A1TP53MAPT
SCHEMBL18561768 0.74 ALDH1A1 (0.33) PGDALDH1A1MAPTPTGS1
SCHEMBL17201497 0.74 TP53 (0.45) TSHRPGDALDH1A1TP53MAPT
SCHEMBL22853564 0.74 ALDH1A1 (0.33) PGDALDH1A1MAPTPTGS1
SCHEMBL9293324 0.74 TSHR (0.47) TSHRPGDALDH1A1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3086396-A1 NONAQUEOUS ELECTROLYTE, CAPACITOR DEVICE USING SAME, AND CARBOXYLIC ACID ESTER COMPOUND USED IN SAME UBE Industries, Ltd. (JP) 2016-10-26 EP disclosed
EP-1058687-B1 NUCLEOSIDES MEDIVIR AB (SE) 2003-12-10 EP disclosed