Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31352071 | 0.81 | TLR7 (0.32) | — | |
| SCHEMBL4233345 | 0.79 | CXCR2 (0.37) | CXCR2CA1CA2CA9P2RX7 | |
| SCHEMBL13239157 | 0.76 | HDAC4 (0.36) | CA1CA2CA9P2RX7NOTUM | |
| SCHEMBL13239154 | 0.75 | FYN (0.32) | CXCR2CA1CA2CA9NOTUM | |
| SCHEMBL13218433 | 0.73 | — | — | |
| SCHEMBL259378 | 0.68 | DRD2 (0.48) | — | |
| SCHEMBL13861488 | 0.64 | CYP1A2 (0.56) | CA1CA2CA9P2RX7NOTUM | |
| SCHEMBL1292950 | 0.63 | — | — | |
| SCHEMBL1292978 | 0.62 | ADORA2A (0.42) | CA1CA2CA9ADORA2A | |
| SCHEMBL18304786 | 0.62 | ADORA2A (0.53) | ADORA2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216763-A1 | Heteroaryl Amide Derivatives | H. LUNDBECK A/S (DK) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216763-A1 | Heteroaryl Amide Derivatives | HCAR2, PIGS, GPR52 | CXCR2 1537/4885CA1 4725/4885CA2 3825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.