SCHEMBL13239285

SCHEMBL13239285

C/C=C/CCc1ccc(-c2ccc(-c3ccc(-c4cc(F)c(F)c(F)c4)c(F)c3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.35
TAAR1 Q96RJ0 1/20 0.35
RARA P10276 1/20 0.35
RARG P13631 1/20 0.35
MAOB P27338 2/20 0.33
CYP17A1 P05093 3/20 0.32
CYP11B1 P15538 2/20 0.32
CYP11B2 P19099 2/20 0.32
KIF11 P52732 1/20 0.31
HCAR2 Q8TDS4 2/20 0.31
CHKA P35790 1/20 0.31
GPR52 Q9Y2T5 1/20 0.30
FDFT1 P37268 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13412054 1.00 RARB (0.35) RARBTAAR1RARARARGMAOB
SCHEMBL13412056 0.91 CHKA (0.33) RARBCHKA
SCHEMBL13412053 0.89 MAOB (0.34) RARBTAAR1RARARARGMAOB
SCHEMBL18458484 0.87 GPR52 (0.40) RARBTAAR1RARARARGHCAR2
SCHEMBL20849604 0.87 GPR52 (0.40) RARBTAAR1RARARARGHCAR2
SCHEMBL15180192 0.87 RARB (0.40) RARBTAAR1RARARARGMAOB
SCHEMBL13577669 0.87 RARB (0.40) RARBTAAR1RARARARGMAOB
SCHEMBL11957385 0.87 FFAR4 (0.39) RARBTAAR1RARARARGKIF11
SCHEMBL16258133 0.87 FFAR4 (0.39) RARBTAAR1RARARARGKIF11
SCHEMBL17402085 0.87 RARB (0.42) RARBTAAR1RARARARGMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2837670-B1 FLUOROBIPHENYL-CONTAINING COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2017-09-27 EP disclosed
US-9441160-B2 Fluorobiphenyl-containing composition DIC CORPORATION (JP) 2016-09-13 US disclosed
US-9441160-B2 Fluorobiphenyl-containing composition DIC CORPORATION (JP) 2016-09-13 US disclosed
US-9181478-B2 Fluorobiphenyl-containing composition DIC CORPORATION (JP) 2015-11-10 US disclosed
US-9181478-B2 Fluorobiphenyl-containing composition DIC CORPORATION (JP) 2015-11-10 US disclosed
US-20150291881-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-10-15 US disclosed
US-20150291881-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-10-15 US disclosed
US-20150252263-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-09-10 US disclosed
US-20150252263-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-09-10 US disclosed
US-20150053891-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-02-26 US disclosed
US-7732021-B2 Liquid crystalline medium MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-06-08 US disclosed
US-7732021-B2 Liquid crystalline medium MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-06-08 US disclosed
US-7635505-B2 Liquid Crystalline Medium MERCK PATENT GMBH (DE) 2009-12-22 US disclosed
US-7635505-B2 Liquid Crystalline Medium MERCK PATENT GMBH (DE) 2009-12-22 US disclosed
US-20090194738-A1 Liquid-crystalline medium MANABE ATSUTAKA 2009-08-06 US disclosed
US-20090194738-A1 Liquid-crystalline medium MANABE ATSUTAKA 2009-08-06 US disclosed
US-20080277623-A1 Liquid Crystalline Medium MERCK PATENT GMBH (DE) 2008-11-13 US disclosed
US-20080277623-A1 Liquid Crystalline Medium MERCK PATENT GMBH (DE) 2008-11-13 US disclosed
US-20080128653-A1 Liquid Crystalline Medium MERCK PATENT GMBH (DE) 2008-06-05 US disclosed
US-20080128653-A1 Liquid Crystalline Medium MERCK PATENT GMBH (DE) 2008-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080277623-A1 Liquid Crystalline Medium CHRM1, NEFM, CCNT1 RARB 2516/4885TAAR1 752/4885RARA 1986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.