SCHEMBL16258133

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11957385	1.00	FFAR4 (0.39)	FFAR4BACE1FFAR1RARBS1PR1
	SCHEMBL15180192	0.89	RARB (0.40)	RARBS1PR1TAAR1RARARARG
	SCHEMBL18458484	0.89	GPR52 (0.40)	FFAR1RARBTAAR1CYP1A2RARA
	SCHEMBL17402085	0.89	RARB (0.42)	RARBS1PR1TAAR1RARARARG
	SCHEMBL15180194	0.89	RARB (0.42)	RARBS1PR1TAAR1RARARARG
	SCHEMBL16258131	0.89	RARB (0.40)	RARBS1PR1TAAR1RARARARG
	SCHEMBL13577669	0.89	RARB (0.40)	RARBS1PR1TAAR1RARARARG
	SCHEMBL20849604	0.89	GPR52 (0.40)	FFAR1RARBTAAR1CYP1A2RARA
	SCHEMBL18854994	0.88	RARB (0.36)	RARBTAAR1RARARARGKIF11
	SCHEMBL13239285	0.87	RARB (0.35)	RARBTAAR1RARARARGGPR52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.