Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPEP1 | P16444 | 10/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13240774 | 1.00 | DPEP1 (0.74) | DPEP1RAB9AMEN1ALDH1A1POLB | |
| SCHEMBL13241007 | 0.85 | DPEP1 (1.00) | DPEP1RAB9APOLBKMT2AMETAP2 | |
| SCHEMBL13241008 | 0.85 | DPEP1 (1.00) | DPEP1RAB9APOLBKMT2AMETAP2 | |
| SCHEMBL13241009 | 0.85 | DPEP1 (1.00) | DPEP1RAB9AKMT2AMETAP2 | |
| SCHEMBL13241006 | 0.85 | DPEP1 (1.00) | DPEP1RAB9AKMT2AMETAP2 | |
| SCHEMBL13240775 | 0.80 | DPEP1 (1.00) | DPEP1METAP2 | |
| SCHEMBL13240771 | 0.78 | DPEP1 (1.00) | DPEP1RAB9A | |
| SCHEMBL13240776 | 0.78 | DPEP1 (1.00) | DPEP1RAB9A | |
| SCHEMBL13240770 | 0.78 | DPEP1 (1.00) | DPEP1RAB9AALDH1A1METAP2 | |
| SCHEMBL13240773 | 0.78 | DPEP1 (1.00) | DPEP1RAB9AALDH1A1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7785564-B2 | an enzyme overexpressed in benign and malignant colon tumors; Aminophosphinic acid derivatives used therapeutically and diagnostically for treatment and detection of tumors | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-08-31 | — | — | US | disclosed |