SCHEMBL13241986

SCHEMBL13241986

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3cccc(C)c3)cc2C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B1 P14061 3/20 0.40
▸ HSD17B2 P37059 3/20 0.40
▸ ENPP3 O14638 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ ACHE P22303 1/20 0.35
▸ NISCH Q9Y2I1 1/20 0.35
▸ CHRNB4 P30926 1/20 0.35
▸ CHRNA3 P32297 1/20 0.35
▸ MAP4K4 O95819 1/20 0.35
▸ AR P10275 1/20 0.35
▸ FYN P06241 1/20 0.35
▸ CLK4 Q9HAZ1 1/20 0.35
▸ DYRK1B Q9Y463 1/20 0.35
▸ SIGMAR1 Q99720 1/20 0.35
▸ CNR1 P21554 1/20 0.35
▸ CNR2 P34972 1/20 0.35
▸ HCRTR2 O43614 1/20 0.35
▸ RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10090595 0.93 HSD17B1 (0.43) HSD17B1HSD17B2ENPP3ACHENISCH
SCHEMBL24525837 0.93 HSD17B1 (0.36) HSD17B1HSD17B2MEN1KMT2AL3MBTL1
SCHEMBL7768344 0.92 HSD17B1 (0.39) HSD17B1HSD17B2MEN1KMT2AACHE
SCHEMBL13136840 0.90 HSD17B1 (0.41) HSD17B1HSD17B2ENPP3ACHESIGMAR1
SCHEMBL142025 0.89 ALDH1A1 (0.39) HSD17B1HSD17B2KMT2AACHEHPGD
SCHEMBL30441321 0.89 ALDH1A1 (0.39) HSD17B1HSD17B2KMT2AACHEHPGD
SCHEMBL14337648 0.89 HSD17B1 (0.38) HSD17B1HSD17B2ACHECNR1CNR2
SCHEMBL7613942 0.88 MEN1 (0.38) HSD17B1HSD17B2MEN1KMT2AL3MBTL1
SCHEMBL14732542 0.88 MEN1 (0.38) HSD17B1HSD17B2MEN1KMT2AL3MBTL1
SCHEMBL12533878 0.88 MEN1 (0.38) HSD17B1HSD17B2MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7764906-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2010-07-27 — — US disclosed
US-7764906-B2 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2010-07-27 — — US disclosed
US-20090104551-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND IMAGE FORMING KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-04-23 — — US disclosed
US-20090104551-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND IMAGE FORMING KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-04-23 — — US disclosed
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