Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242556 | 1.00 | HDAC6 (0.78) | HDAC6KDM4EPOLBHSD17B2CA12 | |
| SCHEMBL1830326 | 0.99 | HDAC6 (0.76) | HDAC6KDM4EPOLBHSD17B2CA12 | |
| SCHEMBL13242559 | 0.96 | HDAC6 (0.71) | HDAC6KDM4EPOLBHSD17B2CA12 | |
| SCHEMBL13242561 | 0.91 | KDM4E (0.67) | HDAC6KDM4EPOLBHSD17B2CA12 | |
| SCHEMBL3366969 | 0.88 | HDAC6 (1.00) | HDAC6KDM4EPOLBHSD17B2MEN1 | |
| SCHEMBL1354888 | 0.88 | HDAC6 (1.00) | HDAC6KDM4EPOLBHSD17B2MEN1 | |
| SCHEMBL1355731 | 0.88 | HDAC6 (1.00) | HDAC6KDM4EPOLBHSD17B2MEN1 | |
| SCHEMBL1354864 | 0.88 | HDAC6 (1.00) | HDAC6KDM4EPOLBHSD17B2MEN1 | |
| SCHEMBL31550983 | 0.88 | HDAC6 (1.00) | HDAC6KDM4EPOLBHSD17B2MEN1 | |
| SCHEMBL1829162 | 0.88 | KDM4E (0.62) | HDAC6KDM4EPOLBHSD17B2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179192-A1 | USE OF NITRIC OXIDE RELEASING COMPOUNDS IN THE TREATMENT OF CHRONIC PAIN | NICOX S.A. (FR) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179192-A1 | USE OF NITRIC OXIDE RELEASING COMPOUNDS IN THE TREATMENT OF CHRONIC PAIN | NOS1, NOS2, NOS3 | HDAC6 1596/4885KDM4E 3010/4885POLB 2055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.