Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12044287 | 0.83 | L3MBTL1 (0.56) | L3MBTL1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL12044225 | 0.77 | KMT2A (0.67) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8522419 | 0.77 | L3MBTL1 (0.72) | L3MBTL1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL6054998 | 0.76 | L3MBTL1 (0.76) | L3MBTL1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL7300382 | 0.76 | L3MBTL1 (0.67) | L3MBTL1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL10863434 | 0.76 | L3MBTL1 (0.71) | L3MBTL1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL28987534 | 0.74 | L3MBTL1 (0.72) | L3MBTL1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL10116581 | 0.72 | L3MBTL1 (0.58) | L3MBTL1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL20511438 | 0.72 | LMNA (0.63) | L3MBTL1KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL10529562 | 0.72 | MEN1 (0.81) | L3MBTL1KDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088408-A2 | SUBUNIT SELECTIVE NMDA RECEPTOR ANTAGONISTS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS | EMORY UNIVERSITY (US) | 2010-08-05 | — | — | WO | disclosed |