Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20543639 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNAKMT2AMAPTHPGD | |
| SCHEMBL3010250 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2APOLBHSD17B10 | |
| SCHEMBL1562037 | 0.74 | ALDH1A1 (0.37) | ALDH1A1LMNAKMT2AMAPTHPGD | |
| SCHEMBL9510197 | 0.72 | ALDH1A1 (0.40) | ALDH1A1LMNAKMT2AMAPTHPGD | |
| SCHEMBL482827 | 0.72 | TDP1 (0.46) | ALDH1A1LMNAKMT2AMAPTHSD17B10 | |
| SCHEMBL7781194 | 0.72 | POLB (0.32) | KMT2APOLBTDP1MEN1 | |
| SCHEMBL1238749 | 0.72 | POLB (0.35) | ALDH1A1LMNAKMT2AMAPTHPGD | |
| SCHEMBL10418773 | 0.72 | ENPEP (0.32) | — | |
| SCHEMBL17787865 | 0.71 | MEN1 (0.40) | ALDH1A1KMT2ARAB9ATDP1MEN1 | |
| SCHEMBL7812076 | 0.71 | ALDH1A1 (0.41) | ALDH1A1LMNAKMT2APOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213638-A1 | Method for the asymmetric hydrogenation of olefins utilising photoisomerisation | DSM IP Assets B.V. (NL) | 2010-08-04 | — | — | EP | disclosed |