Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30707261 | 0.91 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10TDP1HPGD | |
| SCHEMBL27510653 | 0.86 | ALDH1A1 (0.51) | ALDH1A1TP53CYP3A4 | |
| SCHEMBL4013628 | 0.81 | HTT (0.39) | ALDH1A1LMNAHSD17B10HPGDKMT2A | |
| SCHEMBL9255618 | 0.79 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL4138474 | 0.78 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10TDP1KMT2A | |
| SCHEMBL9515535 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNAHPGDKMT2AMAPT | |
| SCHEMBL4139331 | 0.75 | L3MBTL1 (0.36) | ALDH1A1LMNAHSD17B10NPSR1L3MBTL1 | |
| SCHEMBL28326330 | 0.75 | ALDH1A1 (0.47) | ALDH1A1TDP1HPGDKMT2AL3MBTL1 | |
| SCHEMBL8784684 | 0.74 | METAP2 (0.40) | ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL13243290 | 0.72 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559789-A1 | PROCESS FOR THE PREPARATION OF $g(a)-ALKYL LACTONES | HENKEL CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992010487-A1 | PROCESS FOR CONVERTING α-ACYL-SUBSTITUTED LACTONES TO α-ALKYLIDENE-SUBSTITUTED LACTONES | HENKEL CORPORATION (US) | 1992-06-25 | — | — | WO | disclosed |
| WO-1992009590-A1 | PROCESS FOR THE PREPARATION OF α-ALKYL LACTONES | HENKEL CORPORATION (US) | 1992-06-11 | — | — | WO | disclosed |
| EP-0348549-A1 | Improved process for the preparation of substituted furanones | QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) | 1990-01-03 | — | — | EP | disclosed |