Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6023579 | 1.00 | TSHR (0.59) | TSHRTHRBZDHHC7FAAHPOLB | |
| SCHEMBL27621466 | 0.99 | TSHR (0.61) | TSHRTHRBZDHHC7FAAHPOLB | |
| Hydrochloric Acid SCHEMBL1547471 | 0.97 | TSHR (0.59) | TSHRTHRBZDHHC7FAAHPOLB | |
| SCHEMBL2237706 | 0.85 | TSHR (0.54) | TSHRTHRBZDHHC7FAAHGPR84 | |
| SCHEMBL5690541 | 0.79 | TSHR (0.67) | TSHRTHRBFAAHGPR84 | |
| SCHEMBL8776516 | 0.79 | TSHR (0.67) | TSHRTHRBFAAHGPR84 | |
| Bromide SCHEMBL3630569 | 0.78 | TSHR (0.56) | TSHRTHRBZDHHC7 | |
| Trimethylammonium SCHEMBL27612271 | 0.78 | TSHR (0.89) | TSHRTHRBFAAHPOLBAPEX1 | |
| Bromide SCHEMBL28217028 | 0.78 | TSHR (0.96) | TSHRTHRBFAAHPOLBAPEX1 | |
| SCHEMBL20148192 | 0.78 | TSHR (0.65) | TSHRTHRBZDHHC7FAAHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8059997-B2 | Developer carrying member and developing apparatus | CANON KABUSHIKI KAISHA (JP) | 2011-11-15 | — | — | US | disclosed |
| US-20100202801-A1 | DEVELOPER CARRYING MEMBER AND DEVELOPING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2010-08-12 | — | — | US | disclosed |