Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528645 | 0.98 | TSHR (0.62) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL651325 | 0.94 | TSHR (0.75) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL11528248 | 0.94 | TSHR (0.59) | TSHRTHRBTDP1CYP3A4ATM | |
| SCHEMBL4313868 | 0.88 | THRB (0.55) | TSHRTHRBTDP1CYP3A4ATM | |
| SCHEMBL27564296 | 0.88 | TSHR (0.61) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL2817127 | 0.87 | TSHR (0.64) | TSHRTHRBTDP1CYP3A4ATM | |
| SCHEMBL6684134 | 0.87 | TSHR (0.80) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL8169202 | 0.87 | TSHR (0.80) | TSHRTHRBPRSS1PRSS2PRSS3 | |
| SCHEMBL22567351 | 0.87 | TSHR (0.62) | TSHRTHRBTDP1CYP3A4ATM | |
| SCHEMBL11584823 | 0.87 | TSHR (0.53) | TSHRTHRBTDP1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134983-A1 | ULTRA-FLUID LUBRICATING COMPOSITION | TOTALENERGIES ONETECH (FR) | 2018-05-17 | — | — | US | disclosed |