Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18691206 | 1.00 | PTPN11 (0.37) | PTPN11P2RY6NPC1RAB9AHPGD | |
| SCHEMBL18691208 | 1.00 | PTPN11 (0.37) | PTPN11P2RY6NPC1RAB9AHPGD | |
| SCHEMBL13245206 | 0.89 | RARB (0.40) | PTPN11 | |
| SCHEMBL18691202 | 0.89 | RARB (0.40) | PTPN11 | |
| SCHEMBL18691203 | 0.89 | RARB (0.40) | PTPN11 | |
| SCHEMBL14715015 | 0.85 | PTPN11 (0.48) | PTPN11NPC1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL3018699 | 0.83 | PTPN11 (0.47) | PTPN11NPC1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL18712240 | 0.80 | PTPN11 (0.44) | PTPN11NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL3007588 | 0.80 | PTPN11 (0.46) | PTPN11NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3016768 | 0.79 | HPGD (0.44) | PTPN11NPC1RAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | PTPN11 3418/4885P2RY6 2649/4885NPC1 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.