Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 5/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18691202 | 1.00 | RARB (0.40) | RARBRARGHAO1FFAR1CYP26A1 | |
| SCHEMBL18691203 | 1.00 | RARB (0.40) | RARBRARGHAO1FFAR1CYP26A1 | |
| SCHEMBL18691206 | 0.89 | PTPN11 (0.37) | PTPN11 | |
| SCHEMBL18691208 | 0.89 | PTPN11 (0.37) | PTPN11 | |
| SCHEMBL13245133 | 0.89 | PTPN11 (0.37) | PTPN11 | |
| SCHEMBL13245197 | 0.81 | FFAR1 (0.46) | RARBRARGHAO1FFAR1CYP26A1 | |
| SCHEMBL3022123 | 0.80 | FFAR1 (0.45) | RARBRARGHAO1FFAR1CYP26A1 | |
| SCHEMBL18712239 | 0.78 | GRM5 (0.45) | RARBRARGHAO1FFAR1CYP26A1 | |
| SCHEMBL3019877 | 0.76 | FFAR1 (0.46) | RARBRARGHAO1FFAR1CYP26A1 | |
| SCHEMBL3008201 | 0.75 | HAO1 (0.46) | RARBRARGHAO1FFAR1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | RARB 1644/4885RARG 2102/4885HAO1 1626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.